[HTML][HTML] Unraveling plant natural chemical diversity for drug discovery purposes

E Lautie, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

[HTML][HTML] Nitric oxide as a target for phytochemicals in anti-neuroinflammatory prevention therapy

L Subedi, BP Gaire, SY Kim, A Parveen - International journal of …, 2021 - mdpi.com
Nitric oxide (NO) is a neurotransmitter that mediates the activation and inhibition of
inflammatory cascades. Even though physiological NO is required for defense against …

Phytochemicals targeting nitric oxide signaling in neurodegenerative diseases

T Behl, T Rana, A Sehgal, HA Makeen, M Albratty… - Nitric oxide, 2023 - Elsevier
Neurodegenerative diseases are a set of diseases in which slow and progressive neuronal
loss occurs. Nitric oxide (NO) as a neurotransmitter performs key roles in the stimulation and …

Securinega Alkaloids from the Twigs of Securinega suffruticosa and Their Biological Activities

KJ Park, CS Kim, Z Khan, J Oh, SY Kim… - Journal of natural …, 2019 - ACS Publications
Seven new Securinega alkaloids, securingines A–G (1–7), together with seven known
analogues (8–14), were isolated from the twigs of Securinega suffruticosa. Their chemical …

Limonoids from the Fresh Young Leaves and Buds of Toona sinensis and Their Potential Neuroprotective Effects

YH Fu, YT Xie, JM Guo, XP Wang, B Jiang… - Journal of Agricultural …, 2020 - ACS Publications
Toona sinensis, popularly known as Chinese toon or Chinese mahogany, is a perennial
deciduous arbor belonging to the genus Toona in the Meliaceae family, which is widely …

[HTML][HTML] Selected natural products in neuroprotective strategies for Alzheimer's disease—a non-systematic review

K Wojtunik-Kulesza, T Oniszczuk, J Mołdoch… - International Journal of …, 2022 - mdpi.com
Neurodegenerative disorders such as Alzheimer's disease (AD) are distinguished by the
irreversible degeneration of central nervous system function and structure. AD is …

Melongenaterpenes A–L, Vetispirane-Type Sesquiterpenoids from the Roots of Solanum melongena

X Yin, Y Liu, J Pan, HL Ye, Y Sun, DY Zhao… - Journal of natural …, 2019 - ACS Publications
Melongenaterpenes A–L (1–12), 12 new sesquiterpenoids with rare spiro [4.5] decane
skeletons, were isolated from the roots of Solanum melongena. Their 2D structures and …

[HTML][HTML] Anti-Caries Effect of a Mouthwash Containing Sambucus williamsii var. coreana Extract: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

YR Kim, SH Nam - Antibiotics, 2022 - mdpi.com
This study was performed to verify the clinical effect of a mouthwash containing Sambucus
williamsii var. coreana extract on the acid production of oral bacteria and bacteria involved …

Structure elucidation and bioactivities of a new polysaccharide from Xiaojin Boletus speciosus Frost

H Zhu, X Ding, Y Hou, Y Li, M Wang - International journal of biological …, 2019 - Elsevier
A new water-soluble polysaccharide named BSF-X was extracted and purified from the
fruiting bodies of Boletus speciosus Frost which had a molecular weight of 141,309 Da. The …

New iridoids from the roots of Valeriana dioscoridis Sm.

H Kırmızıbekmez, N Kúsz, P Bérdi, I Zupkó, J Hohmann - Fitoterapia, 2018 - Elsevier
Abstract Four new iridoids (1–4), together with three known iridoids (5–7), one known
flavonoid glycoside, three phenolic acids and one phytosterol were isolated from the roots of …