Adaptive thermogenesis in adipocytes: is beige the new brown?

J Wu, P Cohen, BM Spiegelman - Genes & development, 2013 - genesdev.cshlp.org
One of the most promising areas in the therapeutics for metabolic diseases centers around
activation of the pathways of energy expenditure. Brown adipose tissue is a particularly …

Adipose‐derived stem cells for tissue engineering and regenerative medicine applications

R Dai, Z Wang, R Samanipour, K Koo… - Stem cells …, 2016 - Wiley Online Library
Adipose‐derived stem cells (ASCs) are a mesenchymal stem cell source with properties of
self‐renewal and multipotential differentiation. Compared to bone marrow‐derived stem …

Quantifying size and number of adipocytes in adipose tissue

SD Parlee, SI Lentz, H Mori, OA MacDougald - Methods in enzymology, 2014 - Elsevier
White adipose tissue (WAT) is a dynamic and modifiable tissue that develops late during
gestation in humans and through early postnatal development in rodents. WAT is unique in …

Marrow adipose tissue: trimming the fat

EL Scheller, WP Cawthorn, AA Burr… - Trends in Endocrinology …, 2016 - cell.com
Marrow adipose tissue (MAT) is a unique fat depot, located in the skeleton, that has the
potential to contribute to both local and systemic metabolic processes. In this review we …

Specific biological features of adipose tissue, and their impact on HIV persistence

C Bourgeois, J Gorwood, A Barrail-Tran… - Frontiers in …, 2019 - frontiersin.org
Although white AT can contribute to anti-infectious immune responses, it can also be
targeted and perturbed by pathogens. The AT's immune involvement is primarily due to …

Targeting fatty acid metabolism to improve glucose metabolism

R Stinkens, GH Goossens, JWE Jocken… - Obesity …, 2015 - Wiley Online Library
Disturbances in fatty acid metabolism in adipose tissue, liver, skeletal muscle, gut and
pancreas play an important role in the development of insulin resistance, impaired glucose …

Insight into the development of obesity: functional alterations of adipose‐derived mesenchymal stem cells

F Louwen, A Ritter, NN Kreis, J Yuan - Obesity Reviews, 2018 - Wiley Online Library
Obesity is associated with a variety of disorders including cardiovascular diseases, diabetes
mellitus and cancer. Obesity changes the composition and structure of adipose tissue, linked …

The effects of spheroid formation of adipose-derived stem cells in a microgravity bioreactor on stemness properties and therapeutic potential

S Zhang, P Liu, L Chen, Y Wang, Z Wang, B Zhang - Biomaterials, 2015 - Elsevier
Adipose-derived stem cells (ADSCs) represent a valuable source of stem cells for
regenerative medicine, but the loss of their stemness during in vitro expansion remains a …

Adipose-derived stem cells: fatty potentials for therapy

WK Ong, S Sugii - The international journal of biochemistry & cell biology, 2013 - Elsevier
Adipose-derived stem cells (ASCs) are the mesenchymal stem cell (MSC) population found
in the stromal-vascular fraction (SVF) of fat tissue. White adipose tissue (WAT), with well …

Dermal white adipose tissue: a new component of the thermogenic response

CM Alexander, I Kasza, CLE Yen, SB Reeder… - Journal of lipid …, 2015 - ASBMB
Recent literature suggests that the layer of adipocytes embedded in the skin below the
dermis is far from being an inert spacer material. Instead, this layer of dermal white adipose …