Functional architecture of the retina: development and disease

M Hoon, H Okawa, L Della Santina… - Progress in retinal and eye …, 2014 - Elsevier
Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …

[HTML][HTML] Effects and mechanisms of taurine as a therapeutic agent

S Schaffer, HW Kim - Biomolecules & therapeutics, 2018 - ncbi.nlm.nih.gov
Taurine is an abundant, β-amino acid with diverse cytoprotective activity. In some species,
taurine is an essential nutrient but in man it is considered a semi-essential nutrient, although …

Neurodegenerative diseases: implications of environmental and climatic influences on neurotransmitters and neuronal hormones activities

EA Ayeni, AM Aldossary, DA Ayejoto… - International Journal of …, 2022 - mdpi.com
Neurodegenerative and neuronal-related diseases are major public health concerns.
Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal …

VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons

N Froger, F Matonti, C Roubeix, V Forster, I Ivkovic… - Scientific reports, 2020 - nature.com
Vascular endothelial growth factor-A (VEGF) is the angiogenic factor promoting the
pathological neovascularization in age-related macular degeneration (AMD) or diabetic …

Atherosclerosis linked to aberrant amino acid metabolism and immunosuppressive amino acid catabolizing enzymes

BL Zaric, JN Radovanovic, Z Gluvic, AJ Stewart… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular disease is the leading global health concern and responsible for more
deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory …

Taurine and oxidative stress in retinal health and disease

V Castelli, A Paladini, M d'Angelo… - CNS neuroscience & …, 2021 - Wiley Online Library
Retinal disorders are leading causes of blindness and are due to an imbalance between
reactive oxygen species and antioxidant scavenger (in favor of pro‐oxidant species) or a …

Taurine: A source and application for the relief of visual fatigue

H Duan, W Song, J Guo, W Yan - Nutrients, 2023 - mdpi.com
According to reports, supplementation with appropriate doses of taurine may help to reduce
visual fatigue. Presently, some progress has been made in research related to taurine in eye …

The primate model for understanding and restoring vision

S Picaud, D Dalkara, K Marazova… - Proceedings of the …, 2019 - National Acad Sciences
Retinal degenerative diseases caused by photoreceptor cell death are major causes of
irreversible vision loss. As only primates have a macula, the nonhuman primate (NHP) …

Natural products: evidence for neuroprotection to be exploited in glaucoma

A Adornetto, L Rombolà, LA Morrone, C Nucci… - Nutrients, 2020 - mdpi.com
Glaucoma, a leading cause of irreversible blindness worldwide, is an optic neuropathy
characterized by the progressive death of retinal ganglion cells (RGCs). Elevated intraocular …

Taurine: the comeback of a neutraceutical in the prevention of retinal degenerations

N Froger, L Moutsimilli, L Cadetti, F Jammoul… - Progress in retinal and …, 2014 - Elsevier
Taurine is the most abundant amino acid in the retina. In the 1970s, it was thought to be
involved in retinal diseases with photoreceptor degeneration, because cats on a taurine-free …