Cryptococcus neoformans and Cryptococcus gattii species complexes cause
meningoencephalitis with high fatality rates and considerable morbidity, particularly in …

Cryptococcosis is an infectious disease with worldwide distribution and wide array of clinical
presentations caused by pathogenic encapsulated yeasts in the genus Cryptococcus …

Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …

Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

The blood–brain barrier (BBB) is a highly regulated and efficient barrier that provides a
sanctuary to the brain. It is designed to regulate brain homeostasis and to permit selective …

Understanding of the taxonomy and phylogeny of Cryptococcus gattii has been advanced by
modern molecular techniques. C. gattii probably diverged from Cryptococcus neoformans …

Among fungal pathogens, Cryptococcus neoformans has gained great importance among
the scientific community of several reasons. This fungus is the causative agent of …

The outcome of cryptococcal pneumonia correlates with local macrophage polarization
status, as M1 and M2 polarization marks protective and nonprotective responses …

Fungal diseases represent an important paradigm in immunology, as they can result from
either a lack of recognition by the immune system or overactivation of the inflammatory …