Nucleic acid aptamers for molecular diagnostics and therapeutics: advances and perspectives
The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …
Gold nanomaterials at work in biomedicine
Gold is a precious metal with a characteristic bright and beautiful hue known as the golden
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …
Carboxylated chitosan-mediated improved efficacy of mesoporous silica nanoparticle-based targeted drug delivery system for breast cancer therapy
Nanoparticle-based targeting of overexpressed cell-surface receptors is a promising
strategy that provides precise delivery of drugs to cancer cells. In the present study, we …
strategy that provides precise delivery of drugs to cancer cells. In the present study, we …
[HTML][HTML] Hyperthermia and smart drug delivery systems for solid tumor therapy
ALB Seynhaeve, M Amin, D Haemmerich… - Advanced Drug Delivery …, 2020 - Elsevier
Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …
Physical characterization of nanoparticle size and surface modification using particle scattering diffusometry
KN Clayton, JW Salameh, ST Wereley… - …, 2016 - pubs.aip.org
As the field of colloidal science continues to expand, tools for rapid and accurate
physiochemical characterization of colloidal particles will become increasingly important …
physiochemical characterization of colloidal particles will become increasingly important …
Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy
C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …
A highlight of recent advances in aptamer technology and its application
H Sun, Y Zu - Molecules, 2015 - mdpi.com
Aptamers and SELEX (systematic evolution of ligands by exponential enrichment)
technology have gained increasing attention over the past 25 years. Despite their functional …
technology have gained increasing attention over the past 25 years. Despite their functional …
Gold nanoparticles in combinatorial cancer therapy strategies
J Beik, M Khateri, Z Khosravi, SK Kamrava… - Coordination Chemistry …, 2019 - Elsevier
Cancer is one of the most important health issues, which is the second leading cause of
death in the world. Conventional cancer therapy methods encounter with serious drawbacks …
death in the world. Conventional cancer therapy methods encounter with serious drawbacks …
Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications
K Zarschler, L Rocks, N Licciardello, L Boselli… - … , Biology and Medicine, 2016 - Elsevier
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …
between single molecules and classical, larger-sized nanomaterials, not only in terms of …
A comparative analysis of cell surface targeting aptamers
L Kelly, KE Maier, A Yan, M Levy - Nature Communications, 2021 - nature.com
Aptamers represent a potentially important class of ligands for the development of
diagnostics and therapeutics. However, it is often difficult to compare the function and …
diagnostics and therapeutics. However, it is often difficult to compare the function and …