Nucleic acid aptamers for molecular diagnostics and therapeutics: advances and perspectives

L Li, S Xu, H Yan, X Li, HS Yazd, X Li… - Angewandte Chemie …, 2021 - Wiley Online Library
The advent of SELEX (systematic evolution of ligands by exponential enrichment)
technology has shown the ability to evolve artificial ligands with affinity and specificity able to …

Gold nanomaterials at work in biomedicine

X Yang, M Yang, B Pang, M Vara, Y Xia - Chemical reviews, 2015 - ACS Publications
Gold is a precious metal with a characteristic bright and beautiful hue known as the golden
yellow color.(1) As of 2012, a total of 174,100 tons of Au has been mined in human history …

Carboxylated chitosan-mediated improved efficacy of mesoporous silica nanoparticle-based targeted drug delivery system for breast cancer therapy

G Lohiya, DS Katti - Carbohydrate Polymers, 2022 - Elsevier
Nanoparticle-based targeting of overexpressed cell-surface receptors is a promising
strategy that provides precise delivery of drugs to cancer cells. In the present study, we …

[HTML][HTML] Hyperthermia and smart drug delivery systems for solid tumor therapy

ALB Seynhaeve, M Amin, D Haemmerich… - Advanced Drug Delivery …, 2020 - Elsevier
Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …

Physical characterization of nanoparticle size and surface modification using particle scattering diffusometry

KN Clayton, JW Salameh, ST Wereley… - …, 2016 - pubs.aip.org
As the field of colloidal science continues to expand, tools for rapid and accurate
physiochemical characterization of colloidal particles will become increasingly important …

Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

A highlight of recent advances in aptamer technology and its application

H Sun, Y Zu - Molecules, 2015 - mdpi.com
Aptamers and SELEX (systematic evolution of ligands by exponential enrichment)
technology have gained increasing attention over the past 25 years. Despite their functional …

Gold nanoparticles in combinatorial cancer therapy strategies

J Beik, M Khateri, Z Khosravi, SK Kamrava… - Coordination Chemistry …, 2019 - Elsevier
Cancer is one of the most important health issues, which is the second leading cause of
death in the world. Conventional cancer therapy methods encounter with serious drawbacks …

Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications

K Zarschler, L Rocks, N Licciardello, L Boselli… - … , Biology and Medicine, 2016 - Elsevier
Ultrasmall nanoparticulate materials with core sizes in the 1-3 nm range bridge the gap
between single molecules and classical, larger-sized nanomaterials, not only in terms of …

A comparative analysis of cell surface targeting aptamers

L Kelly, KE Maier, A Yan, M Levy - Nature Communications, 2021 - nature.com
Aptamers represent a potentially important class of ligands for the development of
diagnostics and therapeutics. However, it is often difficult to compare the function and …