Cell-culture process optimization via model-based predictions of metabolism and protein glycosylation

JV Reddy, K Raudenbush, ET Papoutsakis… - Biotechnology …, 2023 - Elsevier
In order to meet the rising demand for biologics and become competitive on the developing
biosimilar market, there is a need for process intensification of biomanufacturing processes …

End-to-end process flowsheet modeling for biopharmaceutical production: current state and future potential

NG Malinov, K Raudenbush-Henderson, C Ding… - Current Opinion in …, 2024 - Elsevier
As the biopharmaceutical industry advances to meet the pressures of an expanding product
portfolio and global demand, it will continue to face new challenges while concurrently …