Plant-derived antioxidants protect the nervous system from aging by inhibiting oxidative stress

X Cui, Q Lin, Y Liang - Frontiers in aging neuroscience, 2020 - frontiersin.org
Alzheimer's disease (AD) has become a major disease contributing to human death and is
thought to be closely related to the aging process. The rich antioxidant substances in plants …

Crocin: Functional characteristics, extraction, food applications and efficacy against brain related disorders

A Ali, L Yu, S Kousar, W Khalid, Z Maqbool… - Frontiers in …, 2022 - frontiersin.org
Crocin is a bioactive compound that naturally occurs in some medicinal plants, especially
saffron and gardenia fruit. Different conventional and novel methods are used for its …

Crocin: A fighter against inflammation and pain

M Hashemzaei, C Mamoulakis, K Tsarouhas… - Food and Chemical …, 2020 - Elsevier
Crocin, a water-soluble carotenoid, is known as a pharmacologically active compound,
particularly for its potent anti-oxidant activity. The present work provides a comprehensive …

[HTML][HTML] Effect of alcohol on the central nervous system to develop neurological disorder: pathophysiological and lifestyle modulation can be potential therapeutic …

Z Pervin, JM Stephen - AIMS neuroscience, 2021 - ncbi.nlm.nih.gov
The central nervous system (CNS) is the major target for adverse effects of alcohol and
extensively promotes the development of a significant number of neurological diseases such …

Crocin Alleviates Pain Hyperalgesia in AIA Rats by Inhibiting the Spinal Wnt5a/β‐Catenin Signaling Pathway and Glial Activation

JF Wang, HJ Xu, ZL He, Q Yin, W Cheng - Neural plasticity, 2020 - Wiley Online Library
At present, most of the drugs have little effect on the pathological process of rheumatoid
arthritis (RA). Analgesia is an important measure in the treatment of RA and is also one of …

Saffron carotenoids reversed the UCMS-induced depression and anxiety in rats: Behavioral and biochemical parameters, and hippocampal BDNF/ERK/CREB and …

S Mohammadi, M Naseri, N Faridi, P Zareie, L Zare… - Phytomedicine, 2023 - Elsevier
Background Depression is a debilitating condition that affects the mind and the individual's
body. The improving effects of saffron on depression and anxiety have long been discussed …

Study on the Mechanism for SIRT1 during the Process of Exercise Improving Depression

X Qiu, P Lu, X Zeng, S Jin, X Chen - Brain sciences, 2023 - mdpi.com
The mechanism behind the onset of depression has been the focus of current research in
the neuroscience field. Silent information regulator 1 (SIRT1) is a key player in regulating …

Gardenia yellow pigment: Extraction methods, biological activities, current trends, and future prospects

S Yin, L Niu, J Zhang, Y Liu - Food Research International, 2024 - Elsevier
Food coloring plays a vital role in influencing consumers' food choices, imparting vibrant and
appealing colors to various food and beverage products. Synthetic food colorants have been …

Novel neuroprotective potential of crocin in neurodegenerative disorders: an illustrated mechanistic review

S Kermanshahi, G Ghanavati… - Neurochemical …, 2020 - Springer
Neurodegenerative disorders are characterized by mitochondrial dysfunction and
subsequently oxidative stress, inflammation, and apoptosis that contribute to neuronal …

Preventive effects of crocin, a natural compound from saffron, against nicotine‑induced oxidative stress and neurobehavioral disturbances

M Motaghinejad, M Motevalian… - Acta neurobiologiae …, 2024 - docusalut.com
Nicotine is a psychostimulant that induces neurochemical and behavioral changes upon
chronic administration, leading to neurodegenerative conditions associated with smoking …