[HTML][HTML] Acute kidney injury in the critically ill: an updated review on pathophysiology and management

P Pickkers, M Darmon, E Hoste, M Joannidis… - Intensive care …, 2021 - Springer
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only
affects acute morbidity and mortality, but also a patient's long-term prognosis. In this …

[HTML][HTML] Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality …

JR Prowle, LG Forni, M Bell, MS Chew… - Nature Reviews …, 2021 - nature.com
Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that
is strongly associated with short-term surgical complications and long-term adverse …

Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

J Huang, J Li, Y Lyu, Q Miao, K Pu - Nature materials, 2019 - nature.com
Drug-induced acute kidney injury (AKI) with a high morbidity and mortality is poorly
diagnosed in hospitals and deficiently evaluated in drug discovery. Here, we report the …

[HTML][HTML] Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics

Q Weng, H Sun, C Fang, F Xia, H Liao, J Lee… - Nature …, 2021 - nature.com
Acute kidney injury (AKI) is a prevalent and lethal adverse event that severely affects cancer
patients receiving chemotherapy. It is correlated with the collateral damage to renal cells …

[HTML][HTML] Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference

M Ostermann, R Bellomo, EA Burdmann, K Doi… - Kidney international, 2020 - Elsevier
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the
classification and management of acute kidney injury (AKI). The guideline was derived from …

[HTML][HTML] Acute kidney injury in SARS-CoV-2 infected patients

V Fanelli, M Fiorentino, V Cantaluppi, L Gesualdo… - Critical Care, 2020 - Springer
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the
pathogen responsible of atypical pneumonia that has affected more than 330,000 people …

Renal microvascular endothelial cell responses in sepsis-induced acute kidney injury

G Molema, JG Zijlstra, M van Meurs… - Nature Reviews …, 2022 - nature.com
Microvascular endothelial cells in the kidney have been a neglected cell type in sepsis-
induced acute kidney injury (sepsis-AKI) research; yet, they offer tremendous potential as …

[HTML][HTML] ROS-responsive nano-drug delivery system combining mitochondria-targeting ceria nanoparticles with atorvastatin for acute kidney injury

H Yu, F Jin, D Liu, G Shu, X Wang, J Qi, M Sun… - Theranostics, 2020 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) caused by sepsis is a serious disease which mitochondrial
oxidative stress and inflammatory play a key role in its pathophysiology. Ceria nanoparticles …

[HTML][HTML] Prognostic and predictive enrichment in sepsis

NL Stanski, HR Wong - Nature Reviews Nephrology, 2020 - nature.com
Sepsis is a heterogeneous disease state that is both common and consequential in critically
ill patients. Unfortunately, the heterogeneity of sepsis at the individual patient level has …

[HTML][HTML] A review of challenges and opportunities in machine learning for health

M Ghassemi, T Naumann, P Schulam… - AMIA Summits on …, 2020 - ncbi.nlm.nih.gov
Modern electronic health records (EHRs) provide data to answer clinically meaningful
questions. The growing data in EHRs makes healthcare ripe for the use of machine learning …