Ferrocene-appended pharmacophores: An exciting approach for modulating the biological potential of organic scaffolds

A Singh, I Lumb, V Mehra, V Kumar - Dalton transactions, 2019 - pubs.rsc.org
Two exemplary contributions of organometallics in medicinal chemistry, ferroquine and
ferrocifen, which exhibit excellent anti-plasmodial and anti-cancer activities, respectively …

A study on synthesis of benzodiazepine scaffolds using biologically active chalcones as precursors

AS Bhathiwal, A Bendi, A Tiwari - Journal of Molecular Structure, 2022 - Elsevier
Nowadays, heterocyclic compounds have attained a prominent place among the numerous
classes of aromatic organic compounds in medicinal chemistry due to their important …

Ultrasound promoted stereoselective synthesis of 2, 3-dihydrobenzofuran appended chalcones at ambient temperature

VA Adole, BS Jagdale, TB Pawar, AA Sagane - South african journal of …, 2020 - ajol.info
In the present investigation, an ultrasound promoted the synthesis of a series of (E)-3-(2, 3-
dihydrobenzofuran 5-yl)-1-(aryl) prop-2-en-1-one derivatives from 2, 3-dihydrobenzofuran-5 …

[HTML][HTML] Experimental and Theoretical Studies on the Molecular Structure, FT-IR, NMR, HOMO, LUMO, MESP, and Reactivity Descriptors of (E)-1-(2, 3-Dihydrobenzo …

RA Shinde, VA Adole… - Material Science …, 2020 - materialsciencejournal.org
The present research deals with the synthesis, characterization and density functional theory
(DFT) study of (E)-1-(2, 3-dihydrobenzo [b][1, 4] dioxin-6-yl)-3-(3, 4, 5-trimethoxyphenyl) prop …

Chalcones as anti-infective agents for effective management of tuberculosis

S Mishra, P Jana - Polycyclic Aromatic Compounds, 2024 - Taylor & Francis
After the pandemic COVID-19, global health agencies remind us that tuberculosis is the
deadliest infectious disease worldwide. As per WHO reports, approximately ten million …

Variedly connected 1, 8-naphthalimide-7-chloroquinoline conjugates: Synthesis, anti-mycobacterial and cytotoxic evaluation

MD Johansen, L Kremer, V Kumar - Bioorganic Chemistry, 2019 - Elsevier
Recent disclosures about anti-bacterial and anti-tubercular potential of naphthalimide and
quinoline core respectively propelled us to synthesize a library of 1, 8-naphthalimide-7 …

Design, synthesis, anti‐mycobacterial and cytotoxic evaluation of C‐4 functionalized 1, 8‐naphthalimide‐heterocyclic hydrazide conjugates

Shalini, MD Johansen, L Kremer… - Chemical Biology & …, 2019 - Wiley Online Library
This manuscript discloses the design and synthesis of a series of C‐4 functionalized 1, 8‐
naphthalimide‐heterocyclic hydrazide conjugates along with their anti‐mycobacterial and …

Structural and biological survey of 7‐chloro‐4‐(piperazin‐1‐yl) quinoline and its derivatives

AMAES El‐Azzouny, MN Aboul‐Enein… - Drug Development …, 2020 - Wiley Online Library
Abstract The 7‐chloro‐4‐(piperazin‐1‐yl) quinoline structure is an important scaffold in
medicinal chemistry. It exhibited either alone or as hybrid with other active pharmacophores …

A Study on Biologically Active Chalcone Based Benzodiazepines

A Singh, A Bendi, A Tiwari - IARS'International Research Journal, 2022 - researth.iars.info
Heterocycles that include nitrogen are now indispensable to humanity. The majority of the
major pharmaceuticals on the market are composed of heterocycles that include nitrogen …

[PDF][PDF] INSIGHTS INTO THE POTENTIAL PHARMACOLOGICAL PRACTICES OF CHALCONES: A SHORT REVIEW

VR Bagul - 2021 - researchgate.net
Chalcone is a unique class of organic compounds of great medicinal value since it contains
the flavonoids' reactive enone moiety. Chalcone and its derivatives have medicinal …