The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Nitric oxide (NO⋅), a potentially toxic molecule, has been implicated in a wide range of
biological functions. Details of its biochemistry, however, remain poorly understood. The …

Hydrogen sulfide (H2S), which is well known as a toxic gas, is produced endogenously in
mammalian tissues from L-cysteine mainly by two pyridoxal-5′-phosphate-dependent …

Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …

Indirect evidence suggests accelerated degradation of endothelium-derived nitric oxide
(ENDO) by superoxide anion (O2-) in hypercholesterolemic vessels (HV). To directly …

Endothelium-derived relaxing factor (EDRF) activity has been attributed to the highly labile
nitric oxide radical (NO). In view of the fact that the plasma and cellular milieux contain …

In the Griess reaction, first reported by Johann Peter Griess in 1879 as a method of analysis
of nitrite (NO2−), nitrite reacts under acidic conditions with sulfanilic acid (HO3SC6H4NH2) …

Nitric oxide (NO) is synthesised from l-arginine by the enzyme NO synthase (NOS). The
complex reaction involves the transfer of electrons from NADPH, via the flavins FAD and …

BACKGROUND Endothelium-dependent vasodilation is abnormal in experimental models
of diabetes mellitus. We postulated that abnormalities of endothelial function are also …

A number of lines of evidence suggest that red wine may be more effective than other
alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This …