Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …

Scorpion venom may cause severe medical complications and untimely death if injected into
the human body. Neurotoxins are the main components of scorpion venom that are known to …

The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …

Introduction Cell-penetrating peptide (CPP) technologies represent an important strategy to
address drug delivery to specific intracellular compartments by covalent conjugation to …

Scorpionism is a relevant medical condition in Brazil. It is responsible for most accidents
involving venomous animals in the country, which leads to severe symptoms that can evolve …

The Buthidae family of scorpions consists of arthropods with significant medical relevance,
as their venom contains a diverse range of biomolecules, including neurotoxins that …

Annually, more than 1.2 million scorpion stings and more than 3,000 deaths occur
worldwide. Tityus serrulatus Lutz and Mello, 1922 (Scorpiones, Buthidae) is the most …

Evolution and natural selection have endowed animal venoms, including scorpion venoms,
with a wide range of pharmacological properties. Consequently, scorpions, their venoms …

Background The hyaluronidase enzyme is generally known as a spreading factor in animal
venoms. Although its activity has been demonstrated in several organisms, a deeper …

Tityus cisandinus, a neglected medically important scorpion in Ecuadorian and Peruvian
Amazonia, belongs to a complex of species related to the eastern Amazon endemic Tityus …