[HTML][HTML] From antioxidant to neuromodulator: The role of ascorbate in the management of major depression disorder

NR Ferreira, C Vitorino, A Fortuna - Biochemical Pharmacology, 2022 - Elsevier
Major depressive disorder (MDD) is a debilitating mental illness. For years, the research and
development of drugs to be used in MDD focused on the monoaminergic system, leading to …

Sensorineural hearing loss and cognitive impairment: three hypotheses

H Zhao, Y Wang, L Cui, H Wang, S Liu… - Frontiers in Aging …, 2024 - frontiersin.org
Sensorineural hearing loss (SNHL) is a category of hearing loss that often leads to difficulty
in understanding speech and other sounds. Auditory system dysfunction, including deafness …

[PDF][PDF] A note on the relationships between electronic structure and serotonin 5-HT1A receptor binding affinity in a series of 4-butyl-arylpiperazine-3-(1H-indol-3-yl) …

JS Gómez-Jeria, A Robles-Navarro… - Chemistry Research …, 2021 - chemrj.org
Abstract A Density Functional Theory analysis was performed to investigate the relationships
between 5HT1A receptor affinity and of group of 4-butyl-arylpiperazine-3-(1H-indol-3-yl) …

[HTML][HTML] Excessive level of dietary insect protein negatively changed growth metabolomic and transcriptomic profiles of largemouth bass (Micropterus salmoides)

H Sun, W Dong, G He, Y Long, Y He, Y Chen, S Lin - Animal Nutrition, 2024 - Elsevier
Hermetia illucens (HI) meal is a promising substitute for fish meal (FM) in the feeds of farmed
fish. However, the impacts of dietary HI meal on largemouth bass (LMB) remain unknown. In …

[HTML][HTML] Neurotransmitters: Impressive regulators of tumor progression

Y Yang, L Sun, X Liu, W Liu, Z Zhang, X Zhou… - Biomedicine & …, 2024 - Elsevier
In contemporary times, tumors have emerged as the primary cause of mortality in the global
population. Ongoing research has shed light on the significance of neurotransmitters in the …

UHPLC-MS/MS combined with microdialysis for simultaneous determination of nicotine and neurotransmitter metabolites in the rat hippocampal brain region …

M Zhu, L Cui, G Liu, P Yu, Q Hu, H Chen, H Hou - Analytical Methods, 2024 - pubs.rsc.org
Nicotine crosses the blood–brain barrier and interacts with nicotinic acetylcholine receptors,
initiating a cascade of neurotransmitter effects with potential therapeutic implications for …

[HTML][HTML] The underlying mechanism of calcium toxicity-induced autophagic cell death and lysosomal degradation in early stage of cerebral ischemia

J Sengking, P Mahakkanukrauh - Anatomy & Cell Biology, 2024 - ncbi.nlm.nih.gov
Cerebral ischemia is the important cause of worldwide disability and mortality, that is one of
the obstruction of blood vessels supplying to the brain. In early stage, glutamate …

[HTML][HTML] Indirect Voltammetry Detection of Non-Electroactive Neurotransmitters Using Glassy Carbon Microelectrodes: The Case of Glutamate

SL Galindo, S Nimbalkar, A Oyawale, J Bunnell… - C, 2024 - mdpi.com
Glassy carbon (GC) microelectrodes have been successfully used for the detection of
electroactive neurotransmitters such as dopamine and serotonin through voltammetry …

Integration and comparison of multi-omics profiles of NGLY1 deficiency plasma and cellular models to identify clinically relevant molecular phenotypes

S Chen, G Wang, X Shen, D Hornburg, R Hoffman… - bioRxiv, 2021 - biorxiv.org
Abstract NGLY1 (N-glycanase 1) deficiency is a rare congenital recessive disorder caused
by a mutation in the NGLY1 gene, which encodes the cytosol enzyme N-glycanase 1. The …

[HTML][HTML] Purinergic Signaling in Covid-19 Disease

H Shen - Purinergic System, 2022 - intechopen.com
SARS-CoV-2 virus infection causes the Covid-19 disease pandemic. Purinergic signaling is
a form of extracellular signaling. Purinergic signaling plays significant role in the pathology …