The roles of proteases in prostate cancer
H Koistinen, RM Kovanen, MD Hollenberg… - IUBMB …, 2023 - Wiley Online Library
Since the proposition of the pro‐invasive activity of proteolytic enzymes over 70 years ago,
several roles for proteases in cancer progression have been established. About half of the …
several roles for proteases in cancer progression have been established. About half of the …
Targeting the tumor microenvironment, a new therapeutic approach for prostate cancer
B Fang, Y Lu, X Li, Y Wei, D Ye, G Wei… - Prostate Cancer and …, 2024 - nature.com
Background A growing number of studies have shown that in addition to adaptive immune
cells such as CD8+ T cells and CD4+ T cells, various other cellular components within …
cells such as CD8+ T cells and CD4+ T cells, various other cellular components within …
Fibroblast activation protein (FAP)-mediated cleavage of type III collagen reveals serum biomarker potential in non-small cell lung cancer and spondyloarthritis
RS Pedersen, J Thorlacius-Ussing, MG Raimondo… - Biomedicines, 2024 - mdpi.com
Fibroblast activation protein (FAP) is a known promoter of tumor development and is
associated with poor clinical outcome for various cancer types. Being specifically expressed …
associated with poor clinical outcome for various cancer types. Being specifically expressed …
Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients
R Booijink, LWMM Terstappen, E Dathathri… - Molecular …, 2024 - Wiley Online Library
In prostate cancer (PCa), cancer‐associated fibroblasts (CAFs) promote tumor progression,
drug resistance, and metastasis. Although circulating tumor cells are studied as prognostic …
drug resistance, and metastasis. Although circulating tumor cells are studied as prognostic …
Overexpression of Fibroblast Activation Protein (FAP) in stroma of proliferative inflammatory atrophy (PIA) and primary adenocarcinoma of the prostate
F Caramella Pereira, Q Zheng, J Hicks, S Roy… - medRxiv, 2024 - medrxiv.org
Fibroblast activation protein (FAP) is a serine protease upregulated at sites of tissue
remodeling and cancer that represents a promising therapeutic and molecular imaging …
remodeling and cancer that represents a promising therapeutic and molecular imaging …
Hubungan Nilai Gleason Score dan Grade Groups dengan Ekspresi Fibroblast Activation Protein di Stroma Tumor pada Adenokarsinoma Prostat
Abstract Latar Belakang: Gleason score dan grade groups (GrGp) digunakan sebagai nilai
prognostik adenokarsinoma prostat. Namun, lingkungan mikro tumor yang didominasi oleh …
prognostik adenokarsinoma prostat. Namun, lingkungan mikro tumor yang didominasi oleh …