The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Unravelling the functional operation of neuronal networks and linking cellular activity to
specific behavioural outcomes are among the biggest challenges in neuroscience. In this …

A spinal cord injury interrupts pathways from the brain and brainstem that project to the
lumbar spinal cord, leading to paralysis. Here we show that spatiotemporal epidural …

The episodic nature of locomotion is thought to be controlled by descending inputs from the
brainstem. Most studies have largely attributed this control to initiating excitatory signals, but …

Studies of locomotion in mice suggest that circuits controlling the alternating between left
and right limbs may have a modular organization with distinct locomotor circuits being …

The spinal cord of vertebrate animals is comprised of intrinsic circuits that are capable of
sensing the environment and generating complex motor behaviors. There are two major …

The spinal cord contains neural networks that enable regionally distinct motor outputs along
the body axis. Nevertheless, it remains unclear how segment-specific motor computations …

The coordination and timing of muscle activities during rhythmic movements, like walking
and swimming, are generated by intrinsic spinal motor circuits. Such locomotor networks are …

Sensory circuits in the dorsal spinal cord integrate and transmit multiple cutaneous sensory
modalities including the sense of light touch. Here, we identify a population of excitatory …

Locomotion is controlled by spinal networks that generate rhythm and coordinate left-right
and flexor-extensor patterning. Defined populations of spinal interneurons have been linked …