Diabetes and wound angiogenesis
UA Okonkwo, LA DiPietro - International journal of molecular sciences, 2017 - mdpi.com
Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …
sight. Complications of DM2 involve a myriad of comorbidities including the serious …
Vascular complications in diabetes mellitus: the role of endothelial dysfunction
CG Schalkwijk, CDA Stehouwer - Clinical science, 2005 - portlandpress.com
The endothelium is a complex organ with a multitude of properties essential for control of
vascular functions. Dysfunction of the vascular endothelium is regarded as an important …
vascular functions. Dysfunction of the vascular endothelium is regarded as an important …
[HTML][HTML] Abnormal angiogenesis in diabetic nephropathy
Diabetic retinopathy is the leading cause of blind-ness in the Western world (1) and is
character-ized by abnormal angiogenesis driven by several factors, including tissue …
character-ized by abnormal angiogenesis driven by several factors, including tissue …
p38 mitogen-activated protein kinase downregulates endothelial progenitor cells
FH Seeger, J Haendeler, DH Walter, U Rochwalsky… - Circulation, 2005 - Am Heart Assoc
Background—Transplantation of endothelial progenitor cells (EPCs) improves
neovascularization after ischemia, but patients with coronary artery disease (CAD) or …
neovascularization after ischemia, but patients with coronary artery disease (CAD) or …
[HTML][HTML] Imbalance of angiogenesis in diabetic complications: the mechanisms
Z Tahergorabi, M Khazaei - International journal of preventive …, 2012 - ncbi.nlm.nih.gov
Type 2 diabetes mellitus is a complex disease and a chronic health-care problem.
Nowadays, because of alteration of lifestyle such as lack of exercise, intake of high fat diet …
Nowadays, because of alteration of lifestyle such as lack of exercise, intake of high fat diet …
Aberrant angiogenesis: The gateway to diabetic complications
Diabetes Mellitus is a metabolic cum vascular syndrome with resultant abnormalities in both
micro-and macrovasculature. The adverse long-term effects of diabetes mellitus have been …
micro-and macrovasculature. The adverse long-term effects of diabetes mellitus have been …
Nutrient regulation of cell cycle progression
BL Bohnsack, KK Hirschi - Annu. Rev. Nutr., 2004 - annualreviews.org
▪ Abstract Cell replication is tightly controlled in normal tissues and aberrant during disease
progression, such as in tumorigenesis. The replication of cells can be divided into four …
progression, such as in tumorigenesis. The replication of cells can be divided into four …
Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase
S Kuki, T Imanishi, K Kobayashi, Y Matsuo… - Circulation …, 2006 - jstage.jst.go.jp
Background Both the number and function of bone marrow-derived endothelial progenitor
cells (EPCs) have been shown to be impaired in patients with diabetes mellitus. Therefore …
cells (EPCs) have been shown to be impaired in patients with diabetes mellitus. Therefore …
Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction
S Varma, BK Lal, R Zheng, JW Breslin… - American Journal …, 2005 - journals.physiology.org
Diabetes mellitus is a major risk factor for the development of vascular complications. We
hypothesized that hyperglycemia decreases endothelial cell (EC) proliferation and survival …
hypothesized that hyperglycemia decreases endothelial cell (EC) proliferation and survival …
High glucose promotes retinal endothelial cell migration through activation of Src, PI3K/Akt1/eNOS, and ERKs
Q Huang, N Sheibani - American Journal of Physiology-Cell …, 2008 - journals.physiology.org
Hyperglycemia impacts retinal vascular function and promotes the development and
progression of diabetic retinopathy, which ultimately results in growth of new blood vessels …
progression of diabetic retinopathy, which ultimately results in growth of new blood vessels …