Control of sleep and wakefulness
This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …
Wakefulness promoting systems cause low-voltage, fast activity in the …
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis
WL Smith, Y Urade, PJ Jakobsson - Chemical reviews, 2011 - ACS Publications
Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …
[HTML][HTML] Functions and mechanisms of sleep
MR Zielinski, JT McKenna, RW McCarley - AIMS neuroscience, 2016 - ncbi.nlm.nih.gov
Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …
Arousal effect of orexin A depends on activation of the histaminergic system
ZL Huang, WM Qu, WD Li… - Proceedings of the …, 2001 - National Acad Sciences
Orexin neurons are exclusively localized in the lateral hypothalamic area and project their
fibers to the entire central nervous system, including the histaminergic tuberomammillary …
fibers to the entire central nervous system, including the histaminergic tuberomammillary …
[PDF][PDF] Biochemical regulation of non-rapid-eye-movement sleep
F Obal Jr, JM Krueger - Front Biosci, 2003 - article.imrpress.com
[Frontiers in Bioscience 8, d520-550, May 1, 2003] 520 BIOCHEMICAL REGULATION OF
NON-RAPID-EYE-MOVEMENT SLEEP Ferenc Obal Jr. 1 Page 1 [Frontiers in Bioscience 8 …
NON-RAPID-EYE-MOVEMENT SLEEP Ferenc Obal Jr. 1 Page 1 [Frontiers in Bioscience 8 …
Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase
Y Urade, O Hayaishi - Biochimica et Biophysica Acta (BBA)-Protein …, 2000 - Elsevier
Lipocalin-type prostaglandin (PG) D synthase (PGDS) catalyzes the isomerization of PGH2,
a common precursor of various prostanoids, to produce PGD2, a potent endogenous …
a common precursor of various prostanoids, to produce PGD2, a potent endogenous …
The effects of aging on gene expression in the hypothalamus and cortex of mice
CH Jiang, JZ Tsien, PG Schultz… - Proceedings of the …, 2001 - National Acad Sciences
A better understanding of the molecular effects of aging in the brain may help to reveal
important aspects of organismal aging, as well as processes that lead to age-related brain …
important aspects of organismal aging, as well as processes that lead to age-related brain …
Prostaglandins and sleep–wake regulation
Y Urade, O Hayaishi - Sleep Disorders, 2008 - taylorfrancis.com
In the past 10 years, sleep science has developed remarkably owing to the development of
various types of molecular biological techniques. For example, a sleep center in the …
various types of molecular biological techniques. For example, a sleep center in the …
Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice
Y Fujitani, Y Kanaoka, K Aritake, N Uodome… - The Journal of …, 2002 - journals.aai.org
PGD 2 is a major lipid mediator released from mast cells, but little is known about its role in
the development of allergic reactions. We used transgenic (TG) mice overexpressing human …
the development of allergic reactions. We used transgenic (TG) mice overexpressing human …
T-cell trafficking in asthma: lipid mediators grease the way
AD Luster, AM Tager - Nature Reviews Immunology, 2004 - nature.com
Recruitment of T cells to the airways is crucial in the pathogenesis of asthma, and it is
thought to be mediated mainly by peptide chemokines. By contrast, lipid mediators such as …
thought to be mediated mainly by peptide chemokines. By contrast, lipid mediators such as …