Communication pathways to and from the inner ear and their contributions to drug delivery
AN Salt, K Hirose - Hearing research, 2018 - Elsevier
The environment of the inner ear is highly regulated in a manner that some solutes are
permitted to enter while others are excluded or transported out. Drug therapies targeting the …
permitted to enter while others are excluded or transported out. Drug therapies targeting the …
Responses of the ear to low frequency sounds, infrasound and wind turbines
AN Salt, TE Hullar - Hearing research, 2010 - Elsevier
Infrasonic sounds are generated internally in the body (by respiration, heartbeat, coughing,
etc) and by external sources, such as air conditioning systems, inside vehicles, some …
etc) and by external sources, such as air conditioning systems, inside vehicles, some …
Endolymphatic hydrops: pathophysiology and experimental models
AN Salt, SK Plontke - Otolaryngologic Clinics of North America, 2010 - oto.theclinics.com
Endolymphatic hydrops represents a pathologic anatomic finding in which the structures
bounding the endolymphatic space are distended by an enlargement of endolymphatic …
bounding the endolymphatic space are distended by an enlargement of endolymphatic …
Gene therapy for human sensorineural hearing loss
Hearing loss is the most common sensory impairment in humans and currently disables 466
million people across the world. Congenital deafness affects at least 1 in 500 newborns, and …
million people across the world. Congenital deafness affects at least 1 in 500 newborns, and …
Clinical, oculographic and vestibular test characteristics of Ménière's disease
AS Young, B Nham, AP Bradshaw, Z Calic… - Journal of …, 2022 - Springer
Seventy Ménière's disease (MD) patients with spontaneous vertigo (100%), unilateral aural
fullness (57.1%), tinnitus (78.6%), and subjective hearing loss (75.7%) self-recorded …
fullness (57.1%), tinnitus (78.6%), and subjective hearing loss (75.7%) self-recorded …
[HTML][HTML] The aetiopathologies of Ménière's disease: a contemporary review
BS Oberman, VA Patel, S Cureoglu… - Acta …, 2017 - ncbi.nlm.nih.gov
SUMMARY Ménière's disease, a condition first described in the 1800's, has been an
advancing area of clinical interest and scientific research in recent decades. Guidelines …
advancing area of clinical interest and scientific research in recent decades. Guidelines …
[HTML][HTML] Meniere's disease and vestibular migraine: updates and review of the literature
P Tabet, I Saliba - Journal of clinical medicine research, 2017 - ncbi.nlm.nih.gov
The diagnosis of Meniere's disease (MD) and vestibular migraine (VM) is primarily based on
clinical criteria and their differentiation is often difficult. Currently, there are no known …
clinical criteria and their differentiation is often difficult. Currently, there are no known …
[HTML][HTML] Biomaterials in cochlear implants
T Stöver, T Lenarz - … topics in otorhinolaryngology, head and neck …, 2009 - ncbi.nlm.nih.gov
The cochlear implant (CI) represents, for almost 25 years now, the gold standard in the
treatment of children born deaf and for postlingually deafened adults. These devices thus …
treatment of children born deaf and for postlingually deafened adults. These devices thus …
The basic science of Meniere's disease and endolymphatic hydrops
MT Semaan, KN Alagramam… - Current opinion in …, 2005 - journals.lww.com
Meniere's disease is characterized by the triad of fluctuating hearing loss, episodic vertigo,
and tinnitus and by endolymphatic hydrops found on post-mortem examination. The cause …
and tinnitus and by endolymphatic hydrops found on post-mortem examination. The cause …
[HTML][HTML] Inner ear drug delivery through a cochlear implant: Pharmacokinetics in a Macaque experimental model
R Manrique-Huarte, MA de Linera-Alperi, D Parilli… - Hearing research, 2021 - Elsevier
Objectives The method of drug delivery directly into the cochlea with an implantable pump
connected to a CI electrode array ensures long-term delivery and effective dose control, and …
connected to a CI electrode array ensures long-term delivery and effective dose control, and …