Communication pathways to and from the inner ear and their contributions to drug delivery

AN Salt, K Hirose - Hearing research, 2018 - Elsevier
The environment of the inner ear is highly regulated in a manner that some solutes are
permitted to enter while others are excluded or transported out. Drug therapies targeting the …

Responses of the ear to low frequency sounds, infrasound and wind turbines

AN Salt, TE Hullar - Hearing research, 2010 - Elsevier
Infrasonic sounds are generated internally in the body (by respiration, heartbeat, coughing,
etc) and by external sources, such as air conditioning systems, inside vehicles, some …

Endolymphatic hydrops: pathophysiology and experimental models

AN Salt, SK Plontke - Otolaryngologic Clinics of North America, 2010 - oto.theclinics.com
Endolymphatic hydrops represents a pathologic anatomic finding in which the structures
bounding the endolymphatic space are distended by an enlargement of endolymphatic …

Gene therapy for human sensorineural hearing loss

Y Ren, LD Landegger, KM Stankovic - Frontiers in Cellular …, 2019 - frontiersin.org
Hearing loss is the most common sensory impairment in humans and currently disables 466
million people across the world. Congenital deafness affects at least 1 in 500 newborns, and …

Clinical, oculographic and vestibular test characteristics of Ménière's disease

AS Young, B Nham, AP Bradshaw, Z Calic… - Journal of …, 2022 - Springer
Seventy Ménière's disease (MD) patients with spontaneous vertigo (100%), unilateral aural
fullness (57.1%), tinnitus (78.6%), and subjective hearing loss (75.7%) self-recorded …

[HTML][HTML] The aetiopathologies of Ménière's disease: a contemporary review

BS Oberman, VA Patel, S Cureoglu… - Acta …, 2017 - ncbi.nlm.nih.gov
SUMMARY Ménière's disease, a condition first described in the 1800's, has been an
advancing area of clinical interest and scientific research in recent decades. Guidelines …

[HTML][HTML] Meniere's disease and vestibular migraine: updates and review of the literature

P Tabet, I Saliba - Journal of clinical medicine research, 2017 - ncbi.nlm.nih.gov
The diagnosis of Meniere's disease (MD) and vestibular migraine (VM) is primarily based on
clinical criteria and their differentiation is often difficult. Currently, there are no known …

[HTML][HTML] Biomaterials in cochlear implants

T Stöver, T Lenarz - … topics in otorhinolaryngology, head and neck …, 2009 - ncbi.nlm.nih.gov
The cochlear implant (CI) represents, for almost 25 years now, the gold standard in the
treatment of children born deaf and for postlingually deafened adults. These devices thus …

The basic science of Meniere's disease and endolymphatic hydrops

MT Semaan, KN Alagramam… - Current opinion in …, 2005 - journals.lww.com
Meniere's disease is characterized by the triad of fluctuating hearing loss, episodic vertigo,
and tinnitus and by endolymphatic hydrops found on post-mortem examination. The cause …

[HTML][HTML] Inner ear drug delivery through a cochlear implant: Pharmacokinetics in a Macaque experimental model

R Manrique-Huarte, MA de Linera-Alperi, D Parilli… - Hearing research, 2021 - Elsevier
Objectives The method of drug delivery directly into the cochlea with an implantable pump
connected to a CI electrode array ensures long-term delivery and effective dose control, and …