[HTML][HTML] Sarcopenia–Molecular mechanisms and open questions
P Wiedmer, T Jung, JP Castro, LCD Pomatto… - Ageing research …, 2021 - Elsevier
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …
generalized degenerative loss of skeletal muscle mass, quality, and strength occurring …
Growth hormone (s), testosterone, insulin-like growth factors, and cortisol: roles and integration for cellular development and growth with exercise
WJ Kraemer, NA Ratamess, WC Hymer… - Frontiers in …, 2020 - frontiersin.org
Hormones are largely responsible for the integrated communication of several physiological
systems responsible for modulating cellular growth and development. Although the specific …
systems responsible for modulating cellular growth and development. Although the specific …
Satellite cells and the muscle stem cell niche
Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …
Physical exercise, neuroplasticity, spatial learning and memory
There has long been discussion regarding the positive effects of physical exercise on brain
activity. However, physical exercise has only recently begun to receive the attention of the …
activity. However, physical exercise has only recently begun to receive the attention of the …
The role of the insulin-like growth factor-1 system in breast cancer
IGF-1 is a potent mitogen of major importance in the mammary gland. IGF-1 binding to the
cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti …
cognate receptor, IGF-1R, triggers a signaling cascade leading to proliferative and anti …
Oxidants, antioxidants, and the beneficial roles of exercise‐induced production of reactive species
EC Gomes, AN Silva, MR Oliveira - Oxidative medicine and …, 2012 - Wiley Online Library
This review offers an overview of the influence of reactive species produced during exercise
and their effect on exercise adaptation. Reactive species and free radicals are unstable …
and their effect on exercise adaptation. Reactive species and free radicals are unstable …
Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: roles in skeletal muscle growth and differentiation
The insulin-like growth factor (IGF) signaling pathway consists of multiple IGF ligands, IGF
receptors, and IGF-binding proteins (IGFBPs). Studies in a variety of animal and cellular …
receptors, and IGF-binding proteins (IGFBPs). Studies in a variety of animal and cellular …
Muscle regeneration: cellular and molecular events
M Karalaki, S Fili, A Philippou, M Koutsilieris - In vivo, 2009 - iv.iiarjournals.org
Muscle injury induces strong changes in muscle cells and extracellular matrix. Muscle
regeneration after injury has similarities to muscle development during embryogenesis and …
regeneration after injury has similarities to muscle development during embryogenesis and …
New insights into IGF-1 signaling in the heart
Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy,
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an …
Excitation‐transcription coupling in skeletal muscle: the molecular pathways of exercise
K Gundersen - Biological Reviews, 2011 - Wiley Online Library
Muscle fibres have different properties with respect to force, contraction speed, endurance,
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …
oxidative/glycolytic capacity etc. Although adult muscle fibres are normally post‐mitotic with …