Emerging connections between cerebellar development, behaviour and complex brain disorders

A Sathyanesan, J Zhou, J Scafidi, DH Heck… - Nature Reviews …, 2019 - nature.com
The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

Consensus paper: pathological role of the cerebellum in autism

SH Fatemi, KA Aldinger, P Ashwood, ML Bauman… - The Cerebellum, 2012 - Springer
There has been significant advancement in various aspects of scientific knowledge
concerning the role of cerebellum in the etiopathogenesis of autism. In the current …

A structural MRI study of human brain development from birth to 2 years

RC Knickmeyer, S Gouttard, C Kang… - Journal of …, 2008 - Soc Neuroscience
Brain development in the first 2 years after birth is extremely dynamic and likely plays an
important role in neurodevelopmental disorders, including autism and schizophrenia …

Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits

NL Cerminara, EJ Lang, RV Sillitoe… - Nature Reviews …, 2015 - nature.com
The adult mammalian cerebellar cortex is generally assumed to have a uniform
cytoarchitecture. Differences in cerebellar function are thought to arise primarily through …

Cerebellar modules operate at different frequencies

H Zhou, Z Lin, K Voges, C Ju, Z Gao, LWJ Bosman… - elife, 2014 - elifesciences.org
Due to the uniform cyto-architecture of the cerebellar cortex, its overall physiological
characteristics have traditionally been considered to be homogeneous. In this study, we …

Brain morphology associated with obstructive sleep apnea

PM Macey, LA Henderson, KE Macey… - American journal of …, 2002 - atsjournals.org
Obstructive sleep apnea (OSA) is characterized by repeated occurrences of hypoxic,
hypercapnic, and transient blood pressure elevation episodes that may damage or alter …

Neuropathological findings in autism

SJMC Palmen, H van Engeland, PR Hof, C Schmitz - Brain, 2004 - academic.oup.com
Autism is currently viewed as a largely genetically determined neurodevelopmental
disorder, although its underlying biological causes remain to be established. In this review …

(Patho) physiological significance of the serum-and glucocorticoid-inducible kinase isoforms

F Lang, C Bohmer, M Palmada… - Physiological …, 2006 - journals.physiology.org
The serum-and glucocorticoid-inducible kinase-1 (SGK1) is ubiquitously expressed and
under genomic control by cell stress (including cell shrinkage) and hormones (including …

Brain structural changes in obstructive sleep apnea

PM Macey, R Kumar, MA Woo, EM Valladares… - Sleep, 2008 - academic.oup.com
Abstract Study Objectives: Determine whether obstructive sleep apnea (OSA) subjects show
indications of axonal injury. Design: We assessed fiber integrity in OSA and control subjects …

Clinically distinct electroencephalographic phenotypes of early myoclonus after cardiac arrest

J Elmer, JC Rittenberger, J Faro… - Annals of …, 2016 - Wiley Online Library
Objective We tested the hypothesis that there are readily classifiable
electroencephalographic (EEG) phenotypes of early postanoxic multifocal myoclonus …