The health digital twin to tackle cardiovascular disease—a review of an emerging interdisciplinary field

G Coorey, GA Figtree, DF Fletcher, VJ Snelson… - NPJ digital …, 2022 - nature.com
Potential benefits of precision medicine in cardiovascular disease (CVD) include more
accurate phenotyping of individual patients with the same condition or presentation, using …

Mental stress and cardiovascular health—part I

F Vancheri, G Longo, E Vancheri… - Journal of Clinical …, 2022 - mdpi.com
Epidemiological studies have shown that a substantial proportion of acute coronary events
occur in individuals who lack the traditional high-risk cardiovascular (CV) profile. Mental …

Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data

GA Figtree, ST Vernon, N Hadziosmanovic… - The Lancet, 2021 - thelancet.com
Background In cardiovascular disease, prevention strategies targeting standard modifiable
cardiovascular risk factors (SMuRFs; hypertension, diabetes, hypercholesterolaemia, and …

Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: results from a global meta-analysis of 1,285,722 patients

G Kong, YH Chin, B Chong, RSJ Goh, OZH Lim… - International Journal of …, 2023 - Elsevier
Background Standard modifiable cardiovascular risk factors (SMuRF), comprising diabetes,
hyperlipidemia, hypertension, and smoking, are used for risk stratification in acute coronary …

ST‐segment–elevation myocardial infarction (STEMI) patients without standard modifiable cardiovascular risk factors—how common are they, and what are their …

ST Vernon, S Coffey, M D'Souza, CK Chow… - Journal of the …, 2019 - Am Heart Assoc
Background Programs targeting the standard modifiable cardiovascular risk factors
(SMuRFs: hypertension, diabetes mellitus, hypercholesterolemia, smoking) are critical to …

A call to action for new global approaches to cardiovascular disease drug solutions

GA Figtree, K Broadfoot, B Casadei, R Califf… - European heart …, 2021 - academic.oup.com
Whilst we continue to wrestle with the immense challenge of implementing equitable access
to established evidence-based treatments, substantial gaps remain in our pharmacotherapy …

[HTML][HTML] Prognostic outcomes in acute myocardial infarction patients without standard modifiable risk factors: a multiethnic study of 8,680 Asian patients

G Kong, NWS Chew, CH Ng, YH Chin… - Frontiers in …, 2022 - frontiersin.org
BACKGROUND An increasing proportion of acute myocardial infarction (AMI) patients are
presenting without standard modifiable cardiovascular risk factors (SMuRFs) of …

Same script, different viruses: HIV and COVID-19 in US Black communities

EL Fields, R Copeland, E Hopkins - The Lancet, 2021 - thelancet.com
However, the success of risk stratification and treatment depends on accurate diagnosis and
identification of the underlying disease mechanisms. Several different disease mechanisms …

Genetic, sociodemographic, lifestyle, and clinical risk factors of recurrent coronary artery disease events: a population-based cohort study

SMJ Cho, S Koyama, MC Honigberg… - European Heart …, 2023 - academic.oup.com
Aims Complications of coronary artery disease (CAD) represent the leading cause of death
among adults globally. This study examined the associations and clinical utilities of genetic …

Causes, circumstances, and potential preventability of cardiac arrest in the young: insights from a state-wide clinical and forensic registry

ED Paratz, A van Heusden, D Zentner, N Morgan… - Europace, 2022 - academic.oup.com
Aims The causes, circumstances, and preventability of young sudden cardiac arrest remain
uncertain. Methods and results A prospective state-wide multi-source registry identified all …