Protein–polyelectrolyte interactions

AB Kayitmazer, D Seeman, BB Minsky, PL Dubin, Y Xu - Soft Matter, 2013 - pubs.rsc.org
The interactions of proteins and polyelectrolytes lead to diverse applications in separations,
delivery and wound repair, and are thus of interest to scientists in eg (a) glycobiology,(b) …

Nanoparticles for biomedical imaging

SK Nune, P Gunda, PK Thallapally, YY Lin… - Expert opinion on …, 2009 - Taylor & Francis
Background: Synthetic nanoparticles are emerging as versatile tools in biomedical
applications, particularly in the area of biomedical imaging. Nanoparticles 1–100 nm in …

Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides

H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

Oral bioavailability of insulin contained in polysaccharide nanoparticles

B Sarmento, A Ribeiro, F Veiga, D Ferreira… - …, 2007 - ACS Publications
The pharmacological activity of insulin-loaded dextran sulfate/chitosan nanoparticles was
evaluated following oral dosage in diabetic rats. Nanoparticles were mucoadhesive and …

Multifunctional nanoparticulate polyelectrolyte complexes

SM Hartig, RR Greene, MM Dikov, A Prokop… - Pharmaceutical …, 2007 - Springer
Abstract Water-soluble, biodegradable, polymeric, polyelectrolyte complex dispersions
(PECs) have evolved because of the limitations, in terms of toxicity, of the currently available …

Polyelectrolyte complexes as a “smart” depot for self-healing anticorrosion coatings

DO Grigoriev, K Köhler, E Skorb, DG Shchukin… - Soft Matter, 2009 - pubs.rsc.org
Various types of “intelligent” self-healing anticorrosion coatings using stimuli-responsive
behaviour of polyelectrolyte/inhibitor complexes are presented. Flat nanocomposite …

Nanoparticulation of bovine serum albumin and poly-d-lysine through complex coacervation and encapsulation of curcumin

L Maldonado, R Sadeghi, J Kokini - Colloids and Surfaces B: Biointerfaces, 2017 - Elsevier
Soluble coacervate nanoparticles were fabricated by mixing bovine serum albumin (BSA)
and poly-d-lysine with low (LMW-PDL) and high molecular weights (HMW-PDL). The particle …

Stabilization of polyion complex nanoparticles composed of poly (amino acid) using hydrophobic interactions

T Akagi, K Watanabe, H Kim, M Akashi - Langmuir, 2010 - ACS Publications
We report the design and preparation of polyion complex (PIC) nanoparticles composed of
anionic hydrophobically modified and cationic poly (amino acid) and the effect of …

On the synthesis of mucus permeating nanocarriers

V Bourganis, T Karamanidou, E Samaridou… - European Journal of …, 2015 - Elsevier
The synthesis of nanocarriers with “slippery” surface (ie, poly (lactide-co-glycolide)–
polyethylene glycol (PLGA–PEG) nanoparticles (NPs) and polyelectrolyte complexes …

Recent advances in artificially sulfated polysaccharides for applications in cell growth and differentiation, drug delivery, and tissue engineering

K Zeng, T Groth, K Zhang - ChemBioChem, 2019 - Wiley Online Library
Artificially sulfated polysaccharides, as the mimetics of native heparin and heparan sulfate,
are important bioactive compounds, since they show great potential for tuning crucial …