Background—Infective endocarditis is a potentially lethal disease that has undergone major
changes in both host and pathogen. The epidemiology of infective endocarditis has become …

Infective endocarditis is defined by a focus of infection within the heart and is a feared
disease across the field of cardiology. It is frequently acquired in the health care setting, and …

Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Importance Infective endocarditis occurs in approximately 15 of 100 000 people in the
United States and has increased in incidence. Clinicians must make treatment decisions …

Potential Biases Most studies of IE are affected by selection, survival, and referral bias. They
make it difficult to study the natural history of IE in the general population, because treated …

Importance Limited data exist on clinical characteristics and outcomes of patients who had
infective endocarditis after undergoing transcatheter aortic valve replacement (TAVR) …

Small colony variants (SCVs) were first described more than 100 years ago for
Staphylococcus aureus and various coagulase-negative staphylococci. Two decades ago …

JCS 2017 Guideline on Prevention and Treatment of Infective Endocarditis Toggle navigation
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Purpose: To review the epidemiology of Staphylococcus aureus bacteraemia (SAB) and
endocarditis (SAE), and discuss the short-and long-term outcome. Materials and methods: A …

Infective endocarditis is a relatively rare, but deadly cause of sepsis, with an overall mortality
ranging from 20 to 25% in most series. Although the classic clinical classification into …