Abstract RNA-sequencing (RNA-seq) has a wide variety of applications, but no single
analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data …

Next-generation sequencing (NGS) technologies using DNA, RNA, or methylation
sequencing have impacted enormously on the life sciences. NGS is the choice for large …

Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …

Babelomics has been running for more than one decade offering a user-friendly interface for
the functional analysis of gene expression and genomic data. Here we present its fifth …

The knowledge of the genetic variability of the local population is of utmost importance in
personalized medicine and has been revealed as a critical factor for the discovery of new …

Non-coding RNA transcripts such as microRNAs (miRNAs) and long non-coding RNAs
(lncRNAs) are important genetic regulators. However, the functions of many of these …

The thermophilic fungus Chaetomium thermophilum holds great promise for structural
biology. To increase the efficiency of its biochemical and structural characterization and to …

Whole-exome sequencing has become a fundamental tool for the discovery of disease-
related genes of familial diseases and the identification of somatic driver variants in cancer …

Simple Summary The prognosis of patients with different types of cancer is usually predicted
with the help of the TNM staging guidelines; however, in recent years, there has been …

The Roma are the most numerous ethnic minority in Europe. The Iberian Roma arrived in
the Iberian Peninsula five centuries ago and still today, they keep a strong group identity …