Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

Exploring the phytochemicals and anti-cancer potential of the members of Fabaceae family: A comprehensive review

M Usman, WR Khan, N Yousaf, S Akram, G Murtaza… - Molecules, 2022 - mdpi.com
Cancer is the second-ranked disease and a cause of death for millions of people around the
world despite many kinds of available treatments. Phytochemicals are considered a vital …

Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation

Y Abdalla, A Abdalla, AA Hamza, A Amin - Frontiers in Pharmacology, 2022 - frontiersin.org
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …

Mechanisms of action of fruit and vegetable phytochemicals in colorectal cancer prevention

T Alzate-Yepes, L Pérez-Palacio, E Martínez, M Osorio - Molecules, 2023 - mdpi.com
Colorectal cancer (CRC) is the third most common cancer worldwide and its incidence is
expected to increase by almost 80% by 2030. CRC apparition is related to poor diet, mainly …

Targeting lactate metabolism and glycolytic pathways in the tumor microenvironment by natural products: A promising strategy in combating cancer

L Kooshki, P Mahdavi, S Fakhri, EK Akkol, H Khan - Biofactors, 2022 - Wiley Online Library
Anticancer drugs are not purely effective because of their toxicity, side effects, high cost,
inaccessibility, and associated resistance. On the other hand, cancer is a complex public …

Chemopreventive and anticancer role of resveratrol against oral squamous cell carcinoma

G Angellotti, G Di Prima, E Belfiore, G Campisi… - Pharmaceutics, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) is one of the most prevailing and aggressive head
and neck cancers, featuring high morbidity and mortality. The available conventional …

Therapeutic implications and clinical manifestations of thymoquinone

M Alam, GM Hasan, MM Ansari, R Sharma, DK Yadav… - Phytochemistry, 2022 - Elsevier
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …

Recent trends in extraction, identification and quantification methods of Centella asiatica phytochemicals with potential applications in food industry and therapeutic …

S Tripathy, DK Verma, M Thakur, N Chakravorty… - Food Bioscience, 2022 - Elsevier
Centella asiatica, a pre-historically utilized medicinal herb that is well recognized as a
traditional phytotherapeutic substance for treating a variety of diseases. However, its …

Phytochemicals mediated modulation of microRNAs and long non‐coding RNAs in cancer prevention and therapy

LM Ruiz‐Manriquez, C Estrada‐Meza… - Phytotherapy …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are two main categories of
noncoding RNAs (ncRNAs) that can influence essential biological functions in various ways …