Applications of medicinal chemistry for drug discovery against Acanthamoeba infections

U Ahmed, A Anwar, SK Ong, A Anwar… - Medicinal Research …, 2022 - Wiley Online Library
Acanthamoeba is a genus of free‐living amoebae, pervasively found in the environment.
Most of its pathogenic species are the causative agent of sight‐threatening Acanthamoeba …

Chemometrics approaches in forced degradation studies of pharmaceutical drugs

B Roberto de Alvarenga Junior, R Lajarim Carneiro - Molecules, 2019 - mdpi.com
Chemometrics is the chemistry field responsible for planning and extracting the maximum of
information of experiments from chemical data using mathematical tools (linear algebra …

Design of experiments in pharmaceutical development

AS Dhoot, GJ Fernandes, A Naha… - Pharmaceutical …, 2019 - Springer
In order to develop high-quality pharmaceutical products, a traditional approach based the
univariate or trial and error method was used in the past that led to several problems like …

Advanced core-shell nanostructures based on porous NiCo-P nanodiscs shelled with NiCo-LDH nanosheets as a high-performance electrochemical sensing platform

S Farokhi, M Roushani, H Hosseini - Electrochimica Acta, 2020 - Elsevier
The development of robust and efficient earth-abundant electrocatalysts based on complex
core-shell arrays with ordered two-dimensional nano-architectures for different …

Coupling multi-physics simulation and response surface methodology for the thermal optimization of ternary prismatic lithium-ion battery

H Li, C Liu, A Saini, Y Wang, H Jiang, T Yang… - Journal of Power …, 2019 - Elsevier
A 3D electrochemical-thermal coupled finite element analysis (FEA) model is established on
COMSOL Multiphysics® software for 40 A h ternary prismatic lithium-ion batteries. The input …

Synthesis and characterization of NiCo-X (X= OH, S, Se, P) nanodiscs and comparison of their electrocatalytic performances in an electrochemical sensing platform

S Farokhi, M Roushani, H Hosseini - New Journal of Chemistry, 2022 - pubs.rsc.org
In this paper, NiCo-X (X= OH, S, P, Se) nanodiscs (NDs) were synthesized. Firstly, nickel-
cobalt hydroxide (NiCo-OH) precursors with a nanodisc-like structure were prepared by a …

Extraction of triterpenoid compounds from Ganoderma Lucidum spore powder through a dual-mode sonication process

SF Shen, LF Zhu, Z Wu, G Wang, Z Ahmad… - Drug development …, 2020 - Taylor & Francis
Abstract Development of drug products from natural sources enable advantageous
treatment and therapy options. Bioactive compounds in Ganoderma lucidum spore powder …

Effect of mix proportion parameters on behaviors of basalt fiber RPC based on box-behnken model

H Liu, S Liu, S Wang, X Gao, Y Gong - Applied Sciences, 2019 - mdpi.com
Basalt fibers are widely used in the modification of concrete materials due to its excellent
mechanical properties and corrosion resistance. In this study, the basalt fibers were used to …

Inhibition effects of isoproterenol, chlorpromazine, carbamazepine, tamoxifen drugs on glutathione S-transferase, cholinesterases enzymes and molecular docking …

F Türkan, MH Calimli, GS Kanberoğlu… - Journal of …, 2021 - Taylor & Francis
Nowadays, inhibition of acetylcholinesterase (AChE), butyrylcholinesterase (BChE) and
glutathione S-transferases (GSTs) have been a very crucial issue for pharmacological …

Spectroelectrochemical determination of isoprenaline in a pharmaceutical sample

F Olmo, J Garoz-Ruiz, J Carazo, A Colina, A Heras - Sensors, 2020 - mdpi.com
UV/Vis absorption spectroelectrochemistry (SEC) is a multi-response technique that has
been commonly used for the characterization of materials and the study of reaction …