Emerging microRNA biomarkers for colorectal cancer diagnosis and prognosis

B Chen, Z Xia, YN Deng, Y Yang… - Royal Society …, 2019 - royalsocietypublishing.org
MicroRNAs (miRNAs) are one abundant class of small, endogenous non-coding RNAs,
which regulate various biological processes by inhibiting expression of target genes …

SOX4: epigenetic regulation and role in tumorigenesis

H Hanieh, EA Ahmed, R Vishnubalaji… - Seminars in cancer …, 2020 - Elsevier
Sex-determining region Y-related (SRY) high-mobility group box 4 (SOX4) is a member of
the group C subfamily of SOX transcription factors and promotes tumorigenesis by endowing …

[HTML][HTML] m1A regulated genes modulate PI3K/AKT/mTOR and ErbB pathways in gastrointestinal cancer

Y Zhao, Q Zhao, PJ Kaboli, J Shen, M Li, X Wu… - Translational …, 2019 - Elsevier
BACKGROUND: Gene expression can be posttranscriptionally regulated by a complex
network of proteins. N1-methyladenosine (m1A) is a newly validated RNA modification …

microRNA expression profiling on individual breast cancer patients identifies novel panel of circulating microRNA for early detection

R Hamam, AM Ali, KA Alsaleh, M Kassem, M Alfayez… - Scientific reports, 2016 - nature.com
Breast cancer (BC) is the most common cancer type and the second cause of cancer-related
death among women. Therefore, better understanding of breast cancer tumor biology and …

miR-223-3p inhibits human osteosarcoma metastasis and progression by directly targeting CDH6

Q Ji, X Xu, Q Song, Y Xu, Y Tai, SB Goodman, W Bi… - Molecular Therapy, 2018 - cell.com
Cadherin-6 (CDH6) is aberrantly expressed in cancer and closely associated with tumor
progression. However, the functions of CDH6 in human osteosarcoma and the molecular …

CMC: Cancer miRNA Census–a list of cancer-related miRNA genes

M Suszynska, M Machowska, E Fraszczyk… - Nucleic Acids …, 2024 - academic.oup.com
A growing body of evidence indicates an important role of miRNAs in cancer; however, there
is no definitive, convenient-to-use list of cancer-related miRNAs or miRNA genes that may …

Identification of a 6-gene signature predicting prognosis for colorectal cancer

S Zuo, G Dai, X Ren - Cancer cell international, 2019 - Springer
Background An accurate and robust gene signature is of the utmost importance in assisting
oncologists to make a more accurate evaluation in clinical practice. In our study, we …

Ruptured abdominal aortic aneurysm—epidemiology, predisposing factors, and biology

T Schmitz-Rixen, M Keese, M Hakimi, A Peters… - … archives of surgery, 2016 - Springer
Purpose Abdominal aortic aneurysm is a common degenerative vascular disorder
associated with sudden death due to aortic rupture. This review describes epidemiology …

[HTML][HTML] MicroRNA-320 suppresses colorectal cancer by targeting SOX4, FOXM1, and FOXQ1

R Vishnubalaji, R Hamam, Y Shijun, O Al-Obeed… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most common cancer causing high mortality rates world-
wide. Delineating the molecular mechanisms leading to CRC development and progression …

Joint bioinformatics analysis of underlying potential functions of hsa-let-7b-5p and core genes in human glioma

X Xi, Y Chu, N Liu, Q Wang, Z Yin, Y Lu… - Journal of translational …, 2019 - Springer
Background Glioma accounts for a large proportion of cancer, and an effective treatment for
this disease is still lacking because of the absence of specific driver molecules. Current …