[HTML][HTML] Is increased time to diagnosis and treatment in symptomatic cancer associated with poorer outcomes? Systematic review
RD Neal, P Tharmanathan, B France, NU Din… - British journal of …, 2015 - nature.com
Background: It is unclear whether more timely cancer diagnosis brings favourable outcomes,
with much of the previous evidence, in some cancers, being equivocal. We set out to …
with much of the previous evidence, in some cancers, being equivocal. We set out to …
Delays in diagnosis of paediatric cancers: a systematic review and comparison with expert testimony in lawsuits
JF Brasme, M Morfouace, J Grill, A Martinot… - The lancet …, 2012 - thelancet.com
Delayed diagnosis of paediatric cancers is reported regularly and is a source of remorse for
physicians and parents and a leading cause of malpractice claims. We did a systematic …
physicians and parents and a leading cause of malpractice claims. We did a systematic …
Prevalence of metastasis at diagnosis of osteosarcoma: an international comparison
TA Marko, BJ Diessner, LG Spector - Pediatric blood & cancer, 2016 - Wiley Online Library
Background Osteosarcoma (OS) is the most common primary malignant bone tumor in many
countries, with metastatic disease responsible for most patient deaths. This study compares …
countries, with metastatic disease responsible for most patient deaths. This study compares …
[HTML][HTML] The sarcoma diagnostic interval: a systematic review on length, contributing factors and patient outcomes
V Soomers, O Husson, R Young, I Desar… - ESMO open, 2020 - Elsevier
Sarcomas are rare and heterogeneous mesenchymal tumours of soft tissue or bone, making
them prone to late diagnosis. In other malignancies, early diagnosis has an impact on stage …
them prone to late diagnosis. In other malignancies, early diagnosis has an impact on stage …
A systematic review of time to diagnosis in children and young adults with cancer
CD Lethaby, S Picton, SE Kinsey, R Phillips… - Archives of disease in …, 2013 - adc.bmj.com
Purpose It is often assumed that prolonged time to diagnosis (TTD) for cancer negatively
influences overall survival and survivorship through advanced stage disease at diagnosis …
influences overall survival and survivorship through advanced stage disease at diagnosis …
[HTML][HTML] Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway
Curcumin has potential anticancer activity and has been shown to be involved in several
signaling pathways including differentiation and apoptosis. Our previous study showed that …
signaling pathways including differentiation and apoptosis. Our previous study showed that …
Delay in diagnosis and its effect on clinical outcome in high‐grade sarcoma of bone: a referral oncological centre study
LM Goedhart, JG Gerbers… - Orthopaedic …, 2016 - Wiley Online Library
Objective To investigate delay in diagnosis by both patients and doctors, and to evaluate its
effect on outcomes of high‐grade sarcoma of bone in a single‐referral oncological center …
effect on outcomes of high‐grade sarcoma of bone in a single‐referral oncological center …
[HTML][HTML] Delay in diagnosis of primary osteosarcoma of bone in children: Have we improved in the last 15 years and what is the impact of delay on diagnosis?
S Yoshida, J Celaire, C Pace, C Taylor… - Journal of Bone …, 2021 - Elsevier
Abstract Aims Examine:(1) If length of symptoms (LS) of children with osteosarcoma has
improved in the last 15 years (2) Is delay in diagnosis related to the presence of metastases …
improved in the last 15 years (2) Is delay in diagnosis related to the presence of metastases …
Identification of the novel target genes for osteosarcoma therapy based on comprehensive bioinformatic analysis
X Zhou, Y Fan, W Ye, B Jia, Y Yang, Y Liu - DNA and Cell Biology, 2020 - liebertpub.com
Osteosarcoma is one of the most common primary malignant tumors of the bone and tends
to develop in teenage years. Although multitreatments for the diagnosis and therapy of …
to develop in teenage years. Although multitreatments for the diagnosis and therapy of …
Prognostic impact of diagnostic and treatment delays in children with osteosarcoma
L Vasquez, J Silva, S Chavez, A Zapata… - Pediatric Blood & …, 2020 - Wiley Online Library
Background The aim of this study is to evaluate the relationship between the latency to
diagnosis (LD) and the time to completion of chemotherapy (TCC) with clinical outcomes in …
diagnosis (LD) and the time to completion of chemotherapy (TCC) with clinical outcomes in …