Bromelain is a cysteine protease found in pineapple tissue. Because of its anti‐inflammatory
and anti‐cancer activities, as well as its ability to induce apoptotic cell death, bromelain has …

Introduction As a deadly disease induced by Mycobacterium tuberculosis (Mtb), tuberculosis
remains one of the top killers among infectious diseases. The low intracellular Mtb killing …

Bromelain is a mixture of proteolytic enzymes primarily extracted from the fruit and stem of
the pineapple plant (Ananas comosus). It has a long history of traditional medicinal use in …

The orphan nuclear receptor Nr4a2 is known to modulate both inflammatory and metabolic
processes, but the mechanism by which it regulates innate inflammatory homeostasis has …

Pathogenic mycobacteria orchestrate the complex cell populations known as granuloma that
is the hallmark of tuberculosis. Foam cells, a lipid-rich cell-type, are considered critical for …

Enzymes are very important components which are vital for the existence of every cellular
life. There is significant interest in the use of structurally stable and catalytically active …

A chance discovery of the tumoricidal action of a human milk fraction led to the
characterization of the active component as oleic acid complex of the α-lactalbumin, which …

Recent reports have shown that bromelain (BL), a pineapple extract, acts as an adjuvant
therapy in cancer treatment and prevention of carcinogenesis. The present study was …

In this study, the interaction between four classic dietary antioxidants (including l-ascorbic
acid, α-tocopherol, β-carotene and astaxanthin) and papain/bromelain was investigated by …

Sodium dodecyl sulfate, a biological membrane mimetic, can be used to study the
conversion of globular proteins into amyloid fibrils in vitro. Using multiple approaches, the …