Post-stroke depression: mechanisms and pharmacological treatment

RF Villa, F Ferrari, A Moretti - Pharmacology & therapeutics, 2018 - Elsevier
Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …

[HTML][HTML] Enhancing nervous system recovery through neurobiologics, neural interface training, and neurorehabilitation

MO Krucoff, S Rahimpour, MW Slutzky… - Frontiers in …, 2016 - frontiersin.org
After an initial period of recovery, human neurological injury has long been thought to be
static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or …

[HTML][HTML] Brain–machine interfaces in neurorehabilitation of stroke

SR Soekadar, N Birbaumer, MW Slutzky… - Neurobiology of …, 2015 - Elsevier
Stroke is among the leading causes of long-term disabilities leaving an increasing number
of people with cognitive, affective and motor impairments depending on assistance in their …

[HTML][HTML] Imaging markers of post-stroke depression and apathy: a systematic review and meta-analysis

E Douven, S Köhler, MMF Rodriguez, J Staals… - Neuropsychology …, 2017 - Springer
Several brain imaging markers have been studied in the development of post-stroke
depression (PSD) and post-stroke apathy (PSA), but inconsistent associations have been …

[HTML][HTML] Doenças crônicas não transmissíveis e fatores sociodemográficos associados a sintomas de depressão em idosos

AR Silva, V Sgnaolin, EL Nogueira… - Jornal brasileiro de …, 2017 - SciELO Brasil
Objetivo Investigar a associação das doenças crônicas não transmissíveis e fatores
sociodemográficos com sintomas de depressão em idosos. Métodos Foi realizado um …

[HTML][HTML] Post-stroke depression: impact of lesion location and methodological limitations—a topical review

A Nickel, G Thomalla - Frontiers in neurology, 2017 - frontiersin.org
Post-stroke depression (PSD) affects approximately one-third of all stroke patients. It hinders
rehabilitation and is associated with worse functional outcome and increased mortality …

Large-scale lesion symptom mapping of depression identifies brain regions for risk and resilience

NT Trapp, JE Bruss, K Manzel, J Grafman, D Tranel… - Brain, 2023 - academic.oup.com
Understanding neural circuits that support mood is a central goal of affective neuroscience,
and improved understanding of the anatomy could inform more targeted interventions in …

Altered intrinsic regional brain spontaneous activity and subjective sleep quality in patients with chronic primary insomnia: a resting-state fMRI study

XJ Dai, DC Peng, HH Gong, AL Wan, X Nie… - Neuropsychiatric …, 2014 - Taylor & Francis
Study objective To prospectively explore the underlying regional homogeneity (ReHo) brain-
activity deficit in patients with chronic primary insomnia (PCPIs) and its relationship with …

[HTML][HTML] Neuroinflammation and microglia/macrophage phenotype modulate the molecular background of post-stroke depression: A literature review

EE Nagy, A Frigy, JA Szász… - Experimental and …, 2020 - spandidos-publications.com
Increasing evidence hints to the central role of neuroinflammation in the development of post‑
stroke depression. Danger signals released in the acute phase of ischemia trigger microglial …

[HTML][HTML] Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke

F Vahid-Ansari, DC Lagace, PR Albert - Translational psychiatry, 2016 - nature.com
Post-stroke depression (PSD) is a common outcome following stroke that is associated with
poor recovery. To develop a preclinical model of PSD, we targeted a key node of the …