In a forest of a hundred thousand trees, no two leaves are alike. Similarly, no two cells in a
genetically identical group are the same. This heterogeneity at the single-cell level has been …

Liquid biopsies serve as both powerful noninvasive diagnostic tools for early cancer
screening and prognostic tools for monitoring cancer progression and treatment efficacy …

Stem cells are specialised cells characterised by their unique ability to both self-renew and
transform into a wide array of specialised cell types. The widespread interest in stem cells for …

Human pluripotent stem cells (hPSCs) are a promising source of cells for cell replacement-
based therapies as well as modeling human development and diseases in vitro. However …

Glioblastoma (GBM) is one of the most malignant primary brain tumors. This neoplasm is the
hardest to treat and has a bad prognosis. Because of the characteristics of genetic …

Although the recent advances in stem cell engineering have gained a great deal of attention
due to their high potential in clinical research, the applicability of stem cells for preclinical …

Human stem cell-derived cells and tissues hold considerable potential for applications in
regenerative medicine, disease modeling and drug discovery. The generation, culture and …

Abstract The Aerobic intestinal Host–Anaerobic Microbiota (AHAM) interface is an important
tissue barrier in our intestine where the microbiota resides in close proximity and in …

Human pluripotent stem cells (hPSCs) are important resources for cell-based therapies and
pharmaceutical applications. In order to realize the potential of hPSCs, it is critical to develop …

Mesenchymal stem cells and pluripotent stem cells are recognized as promising tools for
tissue engineering, cell therapy, and drug screening. Their use in therapy requires the …