The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Microplastics and Their Impact on Reproduction—Can we Learn From the C. elegans Model?

E Jewett, G Arnott, L Connolly, N Vasudevan… - Frontiers in …, 2022 - frontiersin.org
Biologically active environmental pollutants have significant impact on ecosystems, wildlife,
and human health. Microplastic (MP) and nanoplastic (NP) particles are pollutants that are …

Estimating entropy production from waiting time distributions

DJ Skinner, J Dunkel - Physical review letters, 2021 - APS
Living systems operate far from thermal equilibrium by converting the chemical potential of
ATP into mechanical work to achieve growth, replication, or locomotion. Given time series …

Brain-wide representations of behavior spanning multiple timescales and states in C. elegans

AA Atanas, J Kim, Z Wang, E Bueno, MC Becker… - Cell, 2023 - cell.com
Changes in an animal's behavior and internal state are accompanied by widespread
changes in activity across its brain. However, how neurons across the brain encode …

Unraveling the dynamics of dopamine release and its actions on target cells

T Sippy, NX Tritsch - Trends in neurosciences, 2023 - cell.com
The neuromodulator dopamine (DA) is essential for regulating learning, motivation, and
movement. Despite its importance, however, the mechanisms by which DA influences the …

Dissecting the functional organization of the C. elegans serotonergic system at whole-brain scale

U Dag, I Nwabudike, D Kang, MA Gomes, J Kim… - Cell, 2023 - cell.com
Serotonin influences many aspects of animal behavior. But how serotonin acts on its diverse
receptors across the brain to modulate global activity and behavior is unknown. Here, we …

Reproductive Aging in Caenorhabditis elegans: From Molecules to Ecology

A Scharf, F Pohl, BM Egan, Z Kocsisova… - Frontiers in cell and …, 2021 - frontiersin.org
Aging animals display a broad range of progressive degenerative changes, and one of the
most fascinating is the decline of female reproductive function. In the model organism …

Host-microbe interactions and the behavior of Caenorhabditis elegans

DH Kim, SW Flavell - Journal of Neurogenetics, 2020 - Taylor & Francis
Microbes are ubiquitous in the natural environment of Caenorhabditis elegans. Bacteria
serve as a food source for C. elegans but may also cause infection in the nematode host …

Learning hydrodynamic equations for active matter from particle simulations and experiments

R Supekar, B Song, A Hastewell… - Proceedings of the …, 2023 - National Acad Sciences
Recent advances in high-resolution imaging techniques and particle-based simulation
methods have enabled the precise microscopic characterization of collective dynamics in …

Dynamic functional connectivity in the static connectome of Caenorhabditis elegans

SW Flavell, A Gordus - Current opinion in neurobiology, 2022 - Elsevier
A hallmark of adaptive behavior is the ability to flexibly respond to sensory cues. To
understand how neural circuits implement this flexibility, it is critical to resolve how a static …