Imaging extracellular vesicles: current and emerging methods
STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
In vivo molecular bioluminescence imaging: new tools and applications
in vivo bioluminescence imaging (BLi) is an optical molecular imaging technique used to
visualize molecular and cellular processes in health and diseases and to follow the fate of …
visualize molecular and cellular processes in health and diseases and to follow the fate of …
Multiplexed epitope-based tissue imaging for discovery and healthcare applications
B Bodenmiller - Cell systems, 2016 - cell.com
The study of organs and tissues on a molecular level is necessary as we seek an
understanding of health and disease. Over the last few years, powerful highly multiplexed …
understanding of health and disease. Over the last few years, powerful highly multiplexed …
Future cancer research priorities in the USA: a Lancet Oncology Commission
EM Jaffee, C Van Dang, DB Agus… - The Lancet …, 2017 - thelancet.com
We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …
biology and cancer. In this era of big data, we are amassing large amounts of information …
In vivo migration of mesenchymal stem cells to burn injury sites and their therapeutic effects in a living mouse model
EJ Oh, HW Lee, S Kalimuthu, TJ Kim, HM Kim… - Journal of Controlled …, 2018 - Elsevier
Mesenchymal stem cell (MSC)-based therapy has emerged as a promising therapeutic
strategy for tissue regeneration and repair. In this study, we non-invasively monitored the …
strategy for tissue regeneration and repair. In this study, we non-invasively monitored the …
Current perspectives on in vivo noninvasive tracking of extracellular vesicles with molecular imaging
P Gangadaran, CM Hong… - BioMed research …, 2017 - Wiley Online Library
Clinical and preclinical in vivo tracking of extracellular vesicles (EVs) are a crucial tool for
the development and optimization of EV‐based diagnosis and treatment. EVs have gained …
the development and optimization of EV‐based diagnosis and treatment. EVs have gained …
Molecular imaging with reporter genes: has its promise been delivered?
I Serganova, RG Blasberg - Journal of Nuclear Medicine, 2019 - Soc Nuclear Med
The first reporter systems were developed in the early 1980s and were based on measuring
the activity of an enzyme—as a surrogate measure of promoter-driven transcriptional activity …
the activity of an enzyme—as a surrogate measure of promoter-driven transcriptional activity …
The immunoimaging toolbox
AT Mayer, SS Gambhir - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
The recent clinical success of cancer immunotherapy has renewed interest in the
development of tools to image the immune system. In general, immunotherapies attempt to …
development of tools to image the immune system. In general, immunotherapies attempt to …
Molecular imaging of innate immunity and immunotherapy
The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …
Advances in Molecular Imaging Strategies for In Vivo Tracking of Immune Cells
HW Lee, P Gangadaran, S Kalimuthu… - BioMed research …, 2016 - Wiley Online Library
Tracking of immune cells in vivo is a crucial tool for development and optimization of cell‐
based therapy. Techniques for tracking immune cells have been applied widely for …
based therapy. Techniques for tracking immune cells have been applied widely for …