Progress on SARS-CoV-2 3CLpro inhibitors: inspiration from SARS-CoV 3CLpro peptidomimetics and small-molecule anti-inflammatory compounds
J Zhu, H Zhang, Q Lin, J Lyu, L Lu, H Chen… - Drug design …, 2023 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) currently poses a threat to human health. 3C-like …
syndrome coronavirus 2 (SARS-CoV-2) currently poses a threat to human health. 3C-like …
Advances in research on 3C-like protease (3CL pro) inhibitors against SARS-CoV-2 since 2020
R Chen, Y Gao, H Liu, H Li, W Chen, J Ma - RSC Medicinal Chemistry, 2023 - pubs.rsc.org
COVID-19 caused by SARS-CoV-2 in late 2019 is still threatening global human health.
Although some vaccines and drugs are available in the market, controlling the spread of the …
Although some vaccines and drugs are available in the market, controlling the spread of the …
Synthesis, crystal structure, computational study and anti-virus effect of mixed ligand copper (II) complex with ONS donor Schiff base and 1, 10-phenanthroline
B Mohan, M Choudhary - Journal of Molecular Structure, 2021 - Elsevier
This work deals with the synthesis, crystal structure, computational study and antiviral
potential of mixed ligand copper (II) complex [Cu (L)(phen)](1),(where, H 2 L=(Z)-N'-((E)-2 …
potential of mixed ligand copper (II) complex [Cu (L)(phen)](1),(where, H 2 L=(Z)-N'-((E)-2 …
A review: The antiviral activity of cyclic peptides
In the design and development of therapeutic agents, macromolecules with restricted
structures have stronger competitive edges than linear biological entities since cyclization …
structures have stronger competitive edges than linear biological entities since cyclization …
Antimicrobial and amyloidogenic activity of peptides. Can antimicrobial peptides be used against SARS-CoV-2?
SR Kurpe, SY Grishin, AK Surin, AV Panfilov… - International Journal of …, 2020 - mdpi.com
At present, much attention is paid to the use of antimicrobial peptides (AMPs) of natural and
artificial origin to combat pathogens. AMPs have several points that determine their …
artificial origin to combat pathogens. AMPs have several points that determine their …
A cyclic peptide inhibitor of the SARS-CoV-2 main protease
This paper presents the design and study of a first-in-class cyclic peptide inhibitor against
the SARS-CoV-2 main protease (M pro). The cyclic peptide inhibitor is designed to mimic the …
the SARS-CoV-2 main protease (M pro). The cyclic peptide inhibitor is designed to mimic the …
Synthesis, molecular docking, and in vivo antidiabetic evaluation of new benzylidene-2, 4-thiazolidinediones as partial PPAR-γ agonists
Peroxisome proliferator-activated receptor-γ (PPAR-γ) partial agonists or antagonists, also
termed as selective PPAR-γ modulators, are more beneficial than full agonists because they …
termed as selective PPAR-γ modulators, are more beneficial than full agonists because they …
Repositioning of anti-dengue compounds against SARS-CoV-2 as viral polyprotein processing inhibitor
A therapy for COVID-19 (Coronavirus Disease 19) caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) remains elusive due to the lack of an effective …
Syndrome Coronavirus 2 (SARS-CoV-2) remains elusive due to the lack of an effective …
Design and molecular docking studies of {N1-[2-(amino)ethyl]ethane-1,2-diamine}-[tris(oxido)]-molybdenum(VI) complex as a potential antivirus drug: from synthesis …
S Kumar, M Choudhary - Journal of Coordination Chemistry, 2023 - Taylor & Francis
The aim of this study was to synthesize and examine the molecular docking of a Mo (VI)
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
complex [Mo (dien) O3](1),{N1-[2-(amino) ethyl] ethane-1, 2-diamine}-[tris (oxido)] …
A multidisciplinary approach to coronavirus disease (COVID-19)
Since December 2019, humanity has faced an important global threat. Many studies have
been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus …
been published on the origin, structure, and mechanism of action of the SARS-CoV-2 virus …