Introduction: Transplantation of autologous mesenchymal stem cells (MSCs) has been
shown to attenuate renal injury and dysfunction in several animal models, and its efficacy is …

Cell-based therapy is a promising strategy for treating chronic kidney disease (CKD) and is
currently the focus of preclinical studies. We performed a systematic review and meta …

Mesenchymal stem/stromal cells (MSCs) have distinct capability for renal repair, but may
have safety concerns. MSC-derived extracellular vesicles emerged as a novel noncellular …

Background Peripheral vascular diseases may induce chronic ischemia and cellular injury
distal to the arterial obstruction. Cellular senescence involves proliferation arrest in …

Background: Extracellular vesicles (EVs) released from mesenchymal stem/stromal cells
(MSCs) mediate their paracrine effect, but their efficacy to protect the microcirculation of the …

Metabolic syndrome (MetS) profoundly changes the contents of mesenchymal stem cells
and mesenchymal stem cells–derived extracellular vesicles (EVs). The anti-inflammatory …

Background Mesenchymal stromal/stem cell (MSC) transplantation is a promising therapy
for tissue regeneration. Extracellular vesicles (EVs) released by MSCs act as their paracrine …

Chronic kidney disease (CKD) is a global health care burden affecting billions of individuals
worldwide. The kidney has limited regenerative capacity from chronic insults, and for the …

In 2017, a new paradigm change caused by artificial intelligence and big data analysis
resulted in innovation in each field of science and technology, and also significantly …

Chronic renal failure is an important clinical problem with significant socioeconomic impact
worldwide. Despite advances in renal replacement therapies and organ transplantation …