The cryopreservation of biomaterials is fundamental to modern biotechnology and
biomedicine, but the biggest challenge is the formation of ice, resulting in fatal cryoinjury to …

Cell-based therapeutics promise to transform the treatment of a wide range of diseases
including cancer, genetic and degenerative disorders, or severe injuries. Many of the …

Cryopreservation of tissues and organs can bring transformative changes to medicine and
medical science. In the past decades, limited progress has been achieved, although …

Glycerol is a major cryoprotective agent and is widely used to promote protein stabilization.
By a combined experimental and theoretical study, we show that global thermodynamic …

The field of assisted reproductive technology (ART) has seen constant improvement and
advancement targeted towards optimal development of the embryos in vitro to improve …

In this paper we show that the shift of the gelatinization temperature of starch in sugar and
polyol solutions is explained by n OH, eff, the volumetric density of hydrogen bonds in the …

In vitro fertilization (IVF) has been one of the most exciting modern medical technologies. It
has transformed the landscape of human infertility treatment. However, current IVF …

Deep eutectic solvents (DESs) emerged as potential alternative solvent media in multiple
areas, including biomolecular (cryo) preservation. Herein, we studied the stability of a small …

In this paper we demonstrate that the denaturation behavior, ie T den, of egg white proteins
in sugar and sugar replacer solutions is explained by the volumetric density of hydrogen …

The structure and interactions of proteins play a critical role in determining the quality
attributes of many foods, beverages, and pharmaceutical products. Incorporating a …