Background Nicotinamide adenine dinucleotide (NAD+), a critical coenzyme present in
every living cell, is involved in a myriad of metabolic processes associated with cellular …

Nicotinamide phosphoribosyltransferase (NAMPT) is a regulator of the intracellular
nicotinamide adenine dinucleotide (NAD) pool. NAD is an essential coenzyme involved in …

Cancer cells have a unique energy metabolism for sustaining rapid proliferation. The
preference for anaerobic glycolysis under normal oxygen conditions is a unique trait of …

Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well
as being a substrate for a number of NAD-consuming enzymes (eg, PARPS, sirtuins, etc) …

Nicotinamide phosphoribosyltransferase (NAMPT) possesses a vital role in mammalian
cells due to its activity as a rate-limiting enzyme in the biosynthesis of nicotinamide adenine …

Tumor cells have increased requirements for NAD+. Thus, many cancers exhibit an
increased reliance on NAD+ production pathways. This dependence may be exploited …

Nicotinamide adenine dinucleotide (NAD) is an essential redox cofactor, but it also acts as a
substrate for NAD-consuming enzymes, regulating cellular events such as DNA repair and …

In this review, we focus on the secreted form of nicotinamide phosphoribosyltransferase
(NAMPT); extracellular NAMPT (eNAMPT), also known as pre‐B cell colony‐enhancing …

The regenerative capacity of the liver is essential for recovery from surgical resection or
injuries induced by trauma or toxins. During liver regeneration, the concentration of …

The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …