Purpose Diabetic peripheral neuropathy (DPN) is the commonest cause of neuropathy
worldwide, and its prevalence increases with the duration of diabetes. It affects …

Diabetic polyneuropathy (DPN) is defined as peripheral nerve dysfunction. There are three
main alterations involved in the pathologic changes of DPN: inflammation, oxidative stress …

Neuropathy will afflict over half of the estimated 460 million people worldwide who have
diabetes, 303 of whom approximately onethird will also develop neuropathic pain. 2 The …

The potential use of stem cell-based therapies for the repair and regeneration of various
tissues and organs is a major goal in repair medicine. Stem cells are classified by their …

Painful diabetic peripheral neuropathy (PDPN) is present in nearly a quarter of people with
diabetes. It is estimated to affect over 100 million people worldwide. PDPN is associated …

Diabetes mellitus (DM) is a major global public health problem that can cause complications
such as diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. Besides the …

Hyperlipidaemia, particularly hypertriglyceridemia, is associated with the development and
progression of neuropathy. Lipid modifying agents may represent a potential therapeutic …

Peripheral neuropathy (PN) is a common disease affecting about 5% of the general
population after the age of 50. Causes of PN are numerous and include genetic, diabetes …

Disruption of mitochondrial function is a common feature of inherited mitochondrial diseases
(mitochondriopathies) and many other infectious and non-infectious diseases including viral …

Diabetic polyneuropathy (DPN) encompasses multiple syndromes with a common
pathogenesis. Glycemic control shows a limited correlation with DPN, arguing in favor of …