Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

The production of melanin significantly enhances the virulence of many important human
pathogenic fungi. Despite fungal melanin's importance in human disease, as well as …

The high mortality of invasive fungal infections, and the limited number and inefficacy of
antifungals necessitate the development of new agents with novel mechanisms and targets …

Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …

Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in
microbial pathogenesis is well established; however, these complex biomolecules also …

The fungal cell wall is a critically important structure that represents a permeability barrier
and protective shield. We probed Candida albicans and Cryptococcus neoformans with …

The cell walls of plants and microbes are a central source for bio-renewable energy and the
major targets of antibiotics and antifungal agents. It is highly challenging to determine the …

Melanin is a ubiquitous natural pigment found in a diverse array of organisms. Allomelanin
is a class of nitrogen-free melanin often found in fungi. Herein, we find artificial allomelanin …

Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

Zygomycetous fungal infections pose an emerging medical threat among individuals with
compromised immunity and metabolic abnormalities. Our pathophysiological understanding …