[HTML][HTML] The traditional Chinese medicines treat chronic heart failure and their main bioactive constituents and mechanisms

J Chen, X Wei, Q Zhang, Y Wu, G Xia, H Xia… - … Pharmaceutica Sinica B, 2023 - Elsevier
Chronic heart failure (CHF) is a severe public health problem with increasing morbidity and
mortality, any treatment targeting a single session is insufficient to tackle this. CHF is …

Phytochemicals mediate autophagy against osteoarthritis by maintaining cartilage homeostasis

Z Tian, X Zhang, M Sun - Frontiers in Pharmacology, 2021 - frontiersin.org
Osteoarthritis (OA) is a common degenerative joint disease and is a leading cause of
disability and reduced quality of life worldwide. There are currently no clinical treatments that …

Exploring active ingredients of anti-osteoarthritis in raw and wine-processed Dipsaci Radix based on spectrum-effect relationship combined with chemometrics

Y Lv, H Wu, Z Hong, F Wei, M Zhao, R Tang, Y Li… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Dipsaci Radix (DR) is the dry root of the Dipsacus
asper Wall. ex DC., which has the function of tonifying the liver and kidney, continuing …

Phytochemical Profiling, Antioxidant Activity, and Protective Effect against H2O2-Induced Oxidative Stress of Carlina vulgaris Extract

I Sowa, J Mołdoch, S Dresler, T Kubrak, A Soluch… - Molecules, 2023 - mdpi.com
Carlina vulgaris is a little-understood plant with unexplored biological potential, and the
papers regarding its chemical composition are scarce. In our study, for the first time, the …

Impact of Chlorogenic Acid on Peripheral Blood Mononuclear Cell Proliferation, Oxidative Stress, and Inflammatory Responses in Racehorses during Exercise

I Dąbrowska, J Grzędzicka, A Niedzielska… - Antioxidants, 2023 - mdpi.com
Green coffee extract is currently of great interest to researchers due to its high concentration
of chlorogenic acid (CGA) and its potential health benefits. CGA constitutes 6 to 10% of the …

Autophagy: an important target for natural products in the treatment of bone metabolic diseases

Z Li, D Li, H Su, H Xue, G Tan, Z Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
Bone homeostasis depends on a precise dynamic balance between bone resorption and
bone formation, involving a series of complex and highly regulated steps. Any imbalance in …

Osteogenic mechanism of chlorogenic acid and its application in clinical practice

J Shen, S Zhang, J Zhang, X Wei, Z Wang… - Frontiers in …, 2024 - frontiersin.org
Natural polyphenols may have a role in counteracting oxidative stress, which is associated
with aging and several bone-related diseases. Chlorogenic acid (CGA) is a naturally …

[HTML][HTML] Non-apoptotic cell death in osteoarthritis: Recent advances and future

P Ji, Z Zhou, J Zhang, T Bai, C Li, B Zhou… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is the most common degenerative joint disease. Multiple tissues are
altered during the development of OA, resulting in joint pain and permanent damage to the …

[HTML][HTML] Chlorogenic acid improves growth performance and intestinal health through autophagy-mediated nuclear factor erythroid 2-related factor 2 pathway in …

H Liu, X Li, S Shi, Y Zhou, K Zhang, Y Wang, J Zhao - Poultry Science, 2022 - Elsevier
The effects of chlorogenic acid (CGA) on growth performance, intestinal morphology,
antioxidant capacity, and the autophagy-mediated nuclear factor erythroid 2-related factor 2 …

Triangular relation of food processing, nutrition, and osteoarthritis: A solution for the management and prevention of osteoarthritis?

A Shahid, AB Altemimi, M Inam-ur-Raheem, R Rabail… - Food Bioscience, 2024 - Elsevier
Osteoarthritis (OA) is the most common and prevalent degenerative disorder of the joints. To
manage OA using a dietary approach, it is crucial to have accurate knowledge of the …