DNA–protein π-interactions in nature: abundance, structure, composition and strength of contacts between aromatic amino acids and DNA nucleobases or …
KA Wilson, JL Kellie, SD Wetmore - Nucleic acids research, 2014 - academic.oup.com
Four hundred twenty-eight high-resolution DNA–protein complexes were chosen for a
bioinformatics study. Although 164 crystal structures (38% of those searched) contained no …
bioinformatics study. Although 164 crystal structures (38% of those searched) contained no …
Synthesis, Binding Properties, and Differences in Cell Uptake of G‐Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates
M Arévalo‐Ruiz, F Doria… - … A European Journal, 2017 - Wiley Online Library
The G‐quadruplexes (G4s) are currently being explored as therapeutic targets in cancer and
other pathologies. Six carbohydrate naphthalene diimide conjugates (carb‐NDIs) have been …
other pathologies. Six carbohydrate naphthalene diimide conjugates (carb‐NDIs) have been …
Recent developments of highly selective sialylation
B Sun - Current Organic Chemistry, 2016 - ingentaconnect.com
Sialic acids usually occur as glycosides of functional glycoconjugates such as
glycoprooteins and glycolips, that are involved in a wide range of biological phenomena, for …
glycoprooteins and glycolips, that are involved in a wide range of biological phenomena, for …
Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G‐quadruplex in K+ Buffer
STG Street, DN Chin, GJ Hollingworth… - … A European Journal, 2017 - Wiley Online Library
Selective G‐quadruplex ligands offer great promise for the development of anti‐cancer
therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively …
therapies. A novel series of divalent cationic naphthalene diimide ligands that selectively …
DNA terminal base pairs have weaker hydrogen bonds especially for AT under low salt concentration
I Ferreira, TD Amarante, G Weber - The Journal of Chemical Physics, 2015 - pubs.aip.org
DNA base pairs are known to open more easily at the helix terminal, a process usually
called end fraying, the details of which are still poorly understood. Here, we present a …
called end fraying, the details of which are still poorly understood. Here, we present a …
Carbohydrate–DNA Interactions at G‐Quadruplexes: Folding and Stability Changes by Attaching Sugars at the 5′‐End
I Gómez‐Pinto, E Vengut‐Climent… - … A European Journal, 2013 - Wiley Online Library
Quadruplex DNA structures are attracting an enormous interest in many areas of chemistry,
ranging from chemical biology, supramolecular chemistry to nanoscience. We have …
ranging from chemical biology, supramolecular chemistry to nanoscience. We have …
Effects of sugar functional groups, hydrophobicity, and fluorination on carbohydrate–DNA stacking interactions in water
R Lucas, P Peñalver, I Gómez-Pinto… - The Journal of …, 2014 - ACS Publications
Carbohydrate–aromatic interactions are highly relevant for many biological processes.
Nevertheless, experimental data in aqueous solution relating structure and energetics for …
Nevertheless, experimental data in aqueous solution relating structure and energetics for …
Synthesis, RNAi activity and nuclease-resistant properties of apolar carbohydrates siRNA conjugates
Oligoribonucleotide conjugates carrying apolar carbohydrates at the 5′-end and the
corresponding siRNA duplexes have been prepared using phosphoramidite chemistry. All …
corresponding siRNA duplexes have been prepared using phosphoramidite chemistry. All …
Three-pronged probes: high-affinity DNA binding with cap, β-alanines and oligopyrrolamides.
R Haug, M Kramer, C Richert - Chemistry-A European …, 2013 - search.ebscohost.com
TPP oligonucleotides: Hybridization probes that interrogate target sequences through base
pairing, stacking on the terminus, and binding in the minor groove are presented (see …
pairing, stacking on the terminus, and binding in the minor groove are presented (see …
Synthesis of carbohydrateoligonucleotide conjugates and their applications
JJ Morales - Enzymatic and chemical synthesis of nucleic acid …, 2018 - books.google.com
Glycolipids and glycoproteins are biomolecules widespread on the cell surface which are
crucial for cell–cell interactions [1] and on the pathogen-cell recognition process [2]. In …
crucial for cell–cell interactions [1] and on the pathogen-cell recognition process [2]. In …