The dormant blood microbiome in chronic, inflammatory diseases
Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …
Chemistry and biology of siderophores
RC Hider, X Kong - Natural product reports, 2010 - pubs.rsc.org
Covering: 1950 up to the end of 2009 Siderophores are compounds produced by bacteria,
fungi and graminaceous plants for scavenging iron from the environment. They are low …
fungi and graminaceous plants for scavenging iron from the environment. They are low …
Iron homeostasis and the inflammatory response
M Wessling-Resnick - Annual review of nutrition, 2010 - annualreviews.org
Iron and its homeostasis are intimately tied to the inflammatory response. The adaptation to
iron deficiency, which confers resistance to infection and improves the inflammatory …
iron deficiency, which confers resistance to infection and improves the inflammatory …
Microbial iron acquisition: marine and terrestrial siderophores
The vast majority of bacteria require iron for growth. 1, 2 Iron is an essential element
required for key biological processes, including amino acid synthesis, oxygen transport …
required for key biological processes, including amino acid synthesis, oxygen transport …
The Yin and Yang of copper during infection
AN Besold, EM Culbertson, VC Culotta - JBIC Journal of Biological …, 2016 - Springer
Copper is an essential micronutrient for both pathogens and the animal hosts they infect.
However, copper can also be toxic in cells due to its redox properties and ability to disrupt …
However, copper can also be toxic in cells due to its redox properties and ability to disrupt …
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's …
DB Kell - Archives of toxicology, 2010 - Springer
Exposure to a variety of toxins and/or infectious agents leads to disease, degeneration and
death, often characterised by circumstances in which cells or tissues do not merely die and …
death, often characterised by circumstances in which cells or tissues do not merely die and …
Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2
Klebsiella pneumoniae is a pathogen of increasing concern because of multidrug
resistance, especially due to K. pneumoniae carbapenemases (KPCs). K. pneumoniae must …
resistance, especially due to K. pneumoniae carbapenemases (KPCs). K. pneumoniae must …
Neutrophil gelatinase-associated lipocalin (NGAL) as biomarker of acute kidney injury: a review of the laboratory characteristics and clinical evidences
A Clerico, C Galli, A Fortunato… - Clinical Chemistry and …, 2012 - degruyter.com
Aldo Clerico graduated in Medicine at the University of Pisa in 1973. He specialized in
endocrinology in 1975, in nuclear medicine in 1978, and in sport medicine in 1987 at the …
endocrinology in 1975, in nuclear medicine in 1978, and in sport medicine in 1987 at the …
The role of iron in the immune response to bacterial infection
BJ Cherayil - Immunologic research, 2011 - Springer
My laboratory has been interested for some time in the influence of iron, a nutrient that is
essential for both microbial pathogens and their mammalian hosts, on the course of …
essential for both microbial pathogens and their mammalian hosts, on the course of …
Trihydroxamate siderophore–fluoroquinolone conjugates are selective sideromycin antibiotics that target Staphylococcus aureus
TA Wencewicz, TE Long, U Möllmann… - Bioconjugate …, 2013 - ACS Publications
Siderophores are multidentate iron (III) chelators used by bacteria for iron assimilation.
Sideromycins, also called siderophore–antibiotic conjugates, are a unique subset of …
Sideromycins, also called siderophore–antibiotic conjugates, are a unique subset of …