Autophagy is an intracellular catabolic pathway in which cellular constituents are engulfed
by autophagosomes and degraded upon autophagosome fusion with lysosomes …

Stressful experiences, both physical and psychological, that are overwhelming (ie,
inescapable and unpredictable), can measurably affect subsequent neuronal properties and …

Uncontrollable stress has been recognized to influence the hippocampus at various levels of
analysis. Behaviorally, human and animal studies have found that stress generally impairs …

Increasing evidence implicates the microbiota in the regulation of brain and behaviour.
Germ‐free mice (GF; microbiota deficient from birth) exhibit altered stress hormone …

Background Hippocampal volume loss is a hallmark of clinical depression. Chronic stress
produces volume loss in the hippocampus in humans and atrophy of CA3 pyramidal cells …

Objective: Although many perinatal factors have been linked to adverse
neurodevelopmental outcomes in very premature infants, much of the variation in outcome …

Major depressive disorder (MDD) has until recently been conceptualized as an episodic
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …

Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

Abstract [Correction Notice: An Erratum for this article was reported in Vol 31 (1) of
Psychology and Aging (see record 2016-06844-004). In the article, the correct analyses …

The neurogenesis hypothesis of depression posits (1) that neurogenesis in the subgranular
zone of the dentate gyrus is regulated negatively by stressful experiences and positively by …