[HTML][HTML] Role of interleukin-6 in depressive disorder

EYC Ting, AC Yang, SJ Tsai - International journal of molecular sciences, 2020 - mdpi.com
Major depressive disorder (MDD), which is a leading psychiatric illness across the world,
severely affects quality of life and causes an increased incidence of suicide. Evidence from …

Inflammatory cytokines in depression: neurobiological mechanisms and therapeutic implications

JC Felger, FE Lotrich - Neuroscience, 2013 - Elsevier
Mounting evidence indicates that inflammatory cytokines contribute to the development of
depression in both medically ill and medically healthy individuals. Cytokines are important …

Elevated C-reactive protein in patients with depression, independent of genetic, health, and psychosocial factors: results from the UK Biobank

MC Pitharouli, SP Hagenaars… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: The authors investigated the pathways (genetic, environmental, lifestyle, medical)
leading to inflammation in major depressive disorder using C-reactive protein (CRP) …

[HTML][HTML] Obesity and inflammation: the linking mechanism and the complications

MS Ellulu, I Patimah, H Khaza'ai… - Archives of medical …, 2017 - ncbi.nlm.nih.gov
Obesity is the accumulation of abnormal or excessive fat that may interfere with the
maintenance of an optimal state of health. The excess of macronutrients in the adipose …

The state of our understanding of the pathophysiology and optimal treatment of depression: glass half full or half empty?

CB Nemeroff - American Journal of Psychiatry, 2020 - Am Psychiatric Assoc
Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

[HTML][HTML] Depression in cancer patients: Pathogenesis, implications and treatment

HR Smith - Oncology letters, 2015 - spandidos-publications.com
Depression is a common comorbidity in cancer cases, affecting> 10% of patients. A cancer
diagnosis is life‑changing, and is a source of considerable psychological and emotional …

A meta-analysis of cytokines in major depression

Y Dowlati, N Herrmann, W Swardfager, H Liu… - Biological …, 2010 - Elsevier
BACKGROUND: Major depression occurs in 4.4% to 20% of the general population. Studies
suggest that major depression is accompanied by immune dysregulation and activation of …

Associations of depression with C-reactive protein, IL-1, and IL-6: a meta-analysis

MB Howren, DM Lamkin, J Suls - Psychosomatic medicine, 2009 - journals.lww.com
Objective: To assess the magnitude and direction of associations of depression with C-
reactive protein (CRP), interleukin (IL)-1, and IL-6 in community and clinical samples …

Cytokines sing the blues: inflammation and the pathogenesis of depression

CL Raison, L Capuron, AH Miller - Trends in immunology, 2006 - cell.com
Increasing amounts of data suggest that inflammatory responses have an important role in
the pathophysiology of depression. Depressed patients have been found to have higher …

[HTML][HTML] Linking what we eat to our mood: a review of diet, dietary antioxidants, and depression

Q Huang, H Liu, K Suzuki, S Ma, C Liu - Antioxidants, 2019 - mdpi.com
Studies have shown that diet and nutrition play significant roles in the prevention of
depression and its clinical treatment. The present review aims to provide a clear …