[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

The endocrine function of adipose tissues in health and cardiometabolic disease

L Scheja, J Heeren - Nature reviews endocrinology, 2019 - nature.com
In addition to their role in glucose and lipid metabolism, adipocytes respond differentially to
physiological cues or metabolic stress by releasing endocrine factors that regulate diverse …

Cytokines and abnormal glucose and lipid metabolism

J Shi, J Fan, Q Su, Z Yang - Frontiers in endocrinology, 2019 - frontiersin.org
Clear evidence indicates that cytokines, for instance, adipokines, hepatokines, inflammatory
cytokines, myokines, and osteokines, contribute substantially to the development of …

Inflammation as a link between periodontal disease and obesity

F Pamuk, A Kantarci - Periodontology 2000, 2022 - Wiley Online Library
Nutrition plays a critical role in the homeostatic balance, maintenance of health, and
longevity. There is a close link between inflammatory diseases and nutritional health …

Obesity-induced changes in adipose tissue microenvironment and their impact on cardiovascular disease

JJ Fuster, N Ouchi, N Gokce, K Walsh - Circulation research, 2016 - Am Heart Assoc
Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

What we talk about when we talk about fat

ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Mechanistic links between obesity, diabetes, and blood pressure: role of perivascular adipose tissue

SN Saxton, BJ Clark, SB Withers… - Physiological …, 2019 - journals.physiology.org
Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Adipokines in inflammation and metabolic disease

N Ouchi, JL Parker, JJ Lugus, K Walsh - Nature reviews immunology, 2011 - nature.com
The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Adipokines in nonalcoholic fatty liver disease

SA Polyzos, J Kountouras, CS Mantzoros - Metabolism, 2016 - Elsevier
Since the discovery of adipose tissue as a higly active endocrine tissue, adipokines,
peptides produced by adipose tissue and exerting autocrine, paracrine and endocrine …

[HTML][HTML] Adipose tissue: physiology to metabolic dysfunction

AJ Richard, U White, CM Elks, JM Stephens - Endotext [Internet], 2020 - ncbi.nlm.nih.gov
Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …