Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Cardiovascular disease (CVD) is the leading cause of death in the world and our approach
to the control and management of CVD mortality is limited. Nattokinase (NK), the most active …

Thrombosis is a principle cause of cardiovascular disease, the leading cause of morbidity
and mortality worldwide; however, the conventional anti-thrombotic approach often leads to …

After thousands of years of evolution and development, traditional fermented soybean foods,
with their unique charm, have gained a stable place in the global market. With the explosive …

Background: Whether soy intake is associated with a decreased risk of cardiovascular
disease (CVD) remains unclear. A traditional Japanese soy food, natto, contains a potent …

Cardiac disorders such as acute myocardial infarction, embolism and stroke are primarily
attributed to excessive fibrin accumulation in the blood vessels, usually consequential in …

Nattokinase (NK), known as a potent fibrinolytic and antithrombotic agent, has been shown
to have antiatherosclerotic and lipid-lowering effects. However, data on human clinical …

Thrombosis has threatened human health in past decades. Bacillus nattokinase is a
potential low-cost thrombolytic drug without side-effects and has been introduced into the …

Our aim was to determine the quantitative effects of a single-dose of Nattokinase (NK)
administration on coagulation/fibrinolysis parameters comprehensively in healthy male …

Nattokinase (NK, also known as subtilisin NAT)(EC 3.4. 21.62) is one of the most
considerable extracellular enzymes produced by Bacillus subtilis natto. The main interest …