There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

Actinobacteria are well-recognised biosynthetic factories that produce an extensive
spectrum of secondary metabolites. Recent genomic insights seem to impact the exploitation …

Throughout history, natural products have played a dominant role in the treatment of human
ailments. For example, the legendary discovery of penicillin transformed global existence …

Naturally produced halogenated compounds are ubiquitous across all domains of life where
they perform a multitude of biological functions and adopt a diversity of chemical structures …

Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …

The prevalence of antimicrobial resistance reduces the effectiveness of antimicrobial drugs
in preventing and treating infectious diseases caused by pathogenic organisms, such as …

Covering: through 2014 Many organisms team up with microbes for defense against
predators, parasites, parasitoids, or pathogens. Here we review the described protective …

Every year, hundreds of new compounds are discovered from the metabolites of marine
organisms. Finding new and useful compounds is one of the crucial drivers for this field of …

Genomic sequence data have revealed the presence of a large fraction of putatively silent
biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary …

Actinomycetes inhabit both terrestrial and marine ecosystems and are highly proficient in
producing a wide range of natural products with diverse biological functions, including …