Effects of the glyphosate-based herbicide Roundup on C. elegans and S. cerevisiae mortality, reproduction, and transcription fidelity

O Dinep-Schneider, E Appiah, A Dapper… - Environmental …, 2024 - Elsevier
Glyphosate-based weed killers such as Roundup have been implicated in detrimental
effects on single-and multicellular eukaryotic model organism health and longevity …

Computing microrna-gene interaction networks in pan-cancer using mirdriver

B Bose, M Moravec, S Bozdag - Scientific Reports, 2022 - nature.com
DNA copy number aberrated regions in cancer are known to harbor cancer driver genes and
the short non-coding RNA molecules, ie, microRNAs. In this study, we integrated the multi …

Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer

M Wagner, M Sobczyński, M Jasek, K Pawełczyk… - BMC cancer, 2023 - Springer
Background ERAP1 is a major aminopeptidase that serves as an editor of the peptide
repertoire by trimming N-terminal residues of antigenic peptides, creating a pool of peptides …

Functional study of the Elongator complex from activity to diseases: characterization of Kti12, a cofactor with a kinase domain

MP Luna - 2021 - theses.hal.science
Alterations of post-transcriptional modifications of RNA play a major role in neurological
disorders and cancer. Of these, mutations affecting the Elongator complex, whose main …

Multiscale Modeling of Cell Fate Switching to Predict Patient-Specific Response to Combination Cancer Therapy

LR Fernandez - 2021 - search.proquest.com
All cells in the human body share the same DNA sequence, but differ in their functional
identity, guided by a wide array of regulatory mechanisms controlling cellular lineage …