Diabetes is a major risk factor for cardiovascular diseases, including diabetic
cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular …

Pathological cardiac hypertrophy is a key risk factor for the development of heart failure and
predisposes individuals to cardiac arrhythmia and sudden death. While physiological …

The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …

Communication between cells is a foundational concept for understanding the physiology
and pathology of biological systems. Paracrine/autocrine signaling, direct cell-to-cell …

In the modern diet, excessive fructose intake (> 50 g/day) had been driven by the increase,
in recent decades, of the consumption of sugar-sweetened beverages. This phenomenon …

Diabetes Mellitus (DM) is a worldwide health issue that can lead to a variety of
complications. DM is a serious metabolic disorder that causes long-term microvascular and …

The metabolic syndrome (MetS) is a constellation of cardiovascular and metabolic
symptoms involving insulin resistance, steatohepatitis, obesity, hypertension, and heart …

Arachidonic acid (AA) has three main metabolic pathways: the cycloxygenases (COXs)
pathway, the lipoxygenases (LOXs) pathway, and the cytochrome P450s (CYPs) pathway …

Abstract Changes in redox state are described in the early stages of ethanol-induced
cardiac toxicity. Here, we evaluated whether nebivolol would abrogate ethanol-induced …

Diabetic nephropathy (DN) is a crucial metabolic health problem. The renin–angiotensin
system (RAS) is well known to play an important role in DN. Abnormal RAS activity can …