Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies
S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …
Mechanisms of action of coffee bioactive compounds–A key to unveil the coffee paradox
F Machado, MA Coimbra, MD Castillo… - Critical reviews in …, 2024 - Taylor & Francis
The knowledge of the relationship between the chemical structure of food components with
their mechanisms of action is crucial for the understanding of diet health benefits. This …
their mechanisms of action is crucial for the understanding of diet health benefits. This …
Neurodegenerative diseases: Can caffeine be a powerful ally to weaken neuroinflammation?
In recent years, there has been considerable research showing that coffee consumption
seems to be beneficial to human health, as it contains a mixture of different bioactive …
seems to be beneficial to human health, as it contains a mixture of different bioactive …
Advances in the understanding of protein misfolding and aggregation through molecular dynamics simulation
Aberrant protein folding known as protein misfolding is counted as one of the striking factors
of neurodegenerative diseases. The extensive range of pathologies caused by protein …
of neurodegenerative diseases. The extensive range of pathologies caused by protein …
Phenylindanes in brewed coffee inhibit amyloid-beta and tau aggregation
RS Mancini, Y Wang, DF Weaver - Frontiers in neuroscience, 2018 - frontiersin.org
Coffee consumption has been correlated with a decreased risk of developing Alzheimer's
disease (AD) and Parkinson's disease (PD), but the mechanism by which coffee may …
disease (AD) and Parkinson's disease (PD), but the mechanism by which coffee may …
ATP Controls the Aggregation of Aβ16–22 Peptides
The oligomerization of Aβ16–22 peptide, which is the hydrophobic core region of full-length
Aβ1–42, causes Alzheimer's disease (AD). This progressive neurodegenerative disease …
Aβ1–42, causes Alzheimer's disease (AD). This progressive neurodegenerative disease …
Molecular simulations of amyloid beta assemblies
G Grasso, A Danani - Advances in Physics: X, 2020 - Taylor & Francis
Several neurodegenerative disorders arise from the abnormal protein aggregation in the
nervous tissue leading tointracellular inclusions or extracellular aggregates in specific brain …
nervous tissue leading tointracellular inclusions or extracellular aggregates in specific brain …
[HTML][HTML] Pharmacology of caffeine and its effects on the human body
Caffeine is the world's most popular stimulant and psychoactive substance. Given the
ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with …
ubiquitous use of caffeine, it is crucial for us to comprehend how our body interacts with …
Comprehending the Efficacy of Whitlock's Caffeine-Pincered Molecular Tweezer on β-Amyloid Aggregation
M Devi, S Paul - ACS Chemical Neuroscience, 2024 - ACS Publications
Alzheimer's disease (AD) stands as one of the most prevalent neurodegenerative
conditions, leading to cognitive impairment, with no cure and preventive measures …
conditions, leading to cognitive impairment, with no cure and preventive measures …
Caffeine destabilizes preformed Aβ protofilaments: Insights from all atom molecular dynamics simulations
S Gupta, AK Dasmahapatra - Physical Chemistry Chemical Physics, 2019 - pubs.rsc.org
The aggregation and deposition of neurotoxic Aβ fibrils are key in the etiology of Alzheimer's
disease (AD). It has been clinically recognized as a major form of dementia across the …
disease (AD). It has been clinically recognized as a major form of dementia across the …