The vascular endothelium is vital in maintaining cardiovascular health by regulating
vascular permeability and tone, preventing thrombosis, and controlling vascular …

The main component of blood and lymphatic vessels is the endothelium covering their
luminal surface. It plays a significant role in many cardiovascular diseases. Tremendous …

Oxidized LDLs (oxLDLs) and oxysterols play a key role in endothelial dysfunction and the
development of atherosclerosis. The loss of vascular endothelium function negatively …

Oxidative stress participates in the development and exacerbation of cardiovascular
diseases (CVD). The ability to promptly quantify an imbalance in an individual reductive …

This review highlights recent findings about the role that endothelial glycocalyx and
caveolae play in vascular homeostasis. We describe the structure, synthesis, and function of …

Reactive oxygen species (ROS) derived from NOX enzymes activity play an important role in
the development of cardiovascular diseases. Compounds able to decrease oxidative stress …

Caveolae are membrane microdomains described in many cell types involved in
endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at …

Endothelial caveolae are essential for a wide range of physiological processes and have
emerged as key players in vascular biology. Our understanding of caveolar biology in …

The cell membrane contains a variety of receptors that interact with signaling molecules.
However, agonist–receptor interactions not always activate a signaling cascade …

Vascular endothelial cells regulate arterial tone through the release of nitric oxide and other
diffusible factors such as prostacyclin and endothelium derived hyperpolarizing factors …